ID B7PYA1_IXOSC Unreviewed; 217 AA.
AC B7PYA1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE SubName: Full=Acetylcholinesterase, putative {ECO:0000313|EMBL:EEC11573.1, ECO:0000313|EnsemblMetazoa:ISCW020834-PA};
DE EC=3.1.1.7 {ECO:0000313|EMBL:EEC11573.1};
GN Name=8033145 {ECO:0000313|EnsemblMetazoa:ISCW020834-PA};
GN ORFNames=IscW_ISCW020834 {ECO:0000313|EMBL:EEC11573.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC11573.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC11573.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW020834-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW020834-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964}.
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DR EMBL; ABJB010374758; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011012472; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS818569; EEC11573.1; -; Genomic_DNA.
DR RefSeq; XP_002402746.1; XM_002402702.1.
DR AlphaFoldDB; B7PYA1; -.
DR PaxDb; 6945-B7PYA1; -.
DR EnsemblMetazoa; ISCW020834-RA; ISCW020834-PA; ISCW020834.
DR KEGG; isc:IscW_ISCW020834; -.
DR VEuPathDB; VectorBase:ISCI020834; -.
DR VEuPathDB; VectorBase:ISCP_023204; -.
DR VEuPathDB; VectorBase:ISCW020834; -.
DR HOGENOM; CLU_1273486_0_0_1; -.
DR InParanoid; B7PYA1; -.
DR OrthoDB; 2474414at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0003990; F:acetylcholinesterase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR PANTHER; PTHR43918; ACETYLCHOLINESTERASE; 1.
DR PANTHER; PTHR43918:SF4; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EEC11573.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487}.
FT DOMAIN 2..151
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 217 AA; 24629 MW; F9170F155BCEB91C CRC64;
MHMFGDMTID CPTNVFTEVA SNQGIKLYRY VFAHRPSFSG WPENYGVTHM DDLAFTLGSL
PFINDSTRFT SPFDSNAQKR LKAAMYTSAE LSFMKEVVAT WTSFIRNGKP SIPLSNEEWP
EYSTSKREGI YLQPQNYTRG RLPRLQECEL WRPILLKGNL MEQVTTGTAK ESQPTKMPDC
VGDPCRSKHL TQINVSAMPK VSCIYLVLLA IITTCCF
//
