ID B7PZN4_IXOSC Unreviewed; 335 AA.
AC B7PZN4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=Nuclear receptor domain-containing protein {ECO:0000259|PROSITE:PS51030};
GN ORFNames=IscW_ISCW008631 {ECO:0000313|EMBL:EEC12056.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC12056.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC12056.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW008631-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW008631-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010847572; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS826936; EEC12056.1; -; Genomic_DNA.
DR RefSeq; XP_002405735.1; XM_002405691.1.
DR AlphaFoldDB; B7PZN4; -.
DR STRING; 6945.B7PZN4; -.
DR PaxDb; 6945-B7PZN4; -.
DR EnsemblMetazoa; ISCW008631-RA; ISCW008631-PA; ISCW008631.
DR KEGG; isc:IscW_ISCW008631; -.
DR VEuPathDB; VectorBase:ISCI008631; -.
DR VEuPathDB; VectorBase:ISCP_037664; -.
DR VEuPathDB; VectorBase:ISCW008631; -.
DR HOGENOM; CLU_043709_0_0_1; -.
DR InParanoid; B7PZN4; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0034056; F:estrogen response element binding; IBA:GO_Central.
DR GO; GO:0004879; F:nuclear receptor activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR48092; KNIRPS-RELATED PROTEIN-RELATED; 1.
DR PANTHER; PTHR48092:SF9; KNIRPS-RELATED PROTEIN-RELATED; 1.
DR Pfam; PF00105; zf-C4; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 25..76
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT REGION 133..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 335 AA; 35815 MW; 7B94989E5C37C2C6 CRC64;
MLQPPAVVVE RAFTAFQNVE FTPGSFFGRT YNNLAALGDC KNSGQCVINK KNRTSCKSCR
LKKCLMVGMS KSGSRYGRRS NWFKIHCLIQ DQAEMNSRIA EQHQLGGAAP QPLTALYDKD
MLGHHYAAKA EEANGTSSPL WSSDKPPSSP ASSYPPPSSS ASTVASTPTA CETKSSNGES
PTNTDAFAYH PMSPVSPISP LHPSKFFFHP GAGVFFGKAP ITHNGLSKLY AEGGGAIAYP
YSPRYLPFGP VKPYRDMLHP STLVVNGECL ADLPEQEGPI DLSVKKAPSP NATPAREGDG
QPAGEDEDVK PAVLAPSSSW AVAEIPLDLR SAKKC
//
