ID B7Q2X4_IXOSC Unreviewed; 58 AA.
AC B7Q2X4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=PCNA-associated factor {ECO:0000256|ARBA:ARBA00013777};
DE AltName: Full=PCNA-associated factor of 15 kDa {ECO:0000256|ARBA:ARBA00030014};
DE AltName: Full=PCNA-clamp-associated factor {ECO:0000256|ARBA:ARBA00031186};
GN ORFNames=IscW_ISCW008908 {ECO:0000313|EMBL:EEC13196.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC13196.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC13196.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW008908-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW008908-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region
CC {ECO:0000256|ARBA:ARBA00004556}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; ABJB010166670; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010944534; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS846584; EEC13196.1; -; Genomic_DNA.
DR RefSeq; XP_002411072.1; XM_002411027.1.
DR AlphaFoldDB; B7Q2X4; -.
DR PaxDb; 6945-B7Q2X4; -.
DR EnsemblMetazoa; ISCW008908-RA; ISCW008908-PA; ISCW008908.
DR KEGG; isc:IscW_ISCW008908; -.
DR VEuPathDB; VectorBase:ISCI008908; -.
DR VEuPathDB; VectorBase:ISCW008908; -.
DR HOGENOM; CLU_2981368_0_0_1; -.
DR InParanoid; B7Q2X4; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR InterPro; IPR040444; PCNA-AF.
DR InterPro; IPR031444; PCNA-AF_dom.
DR PANTHER; PTHR15679; PCNA-ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR15679:SF8; PCNA-ASSOCIATED FACTOR; 1.
DR Pfam; PF15715; PAF; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7Q2X4};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 7..46
FT /note="PCNA-associated factor histone-like"
FT /evidence="ECO:0000259|Pfam:PF15715"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 31..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 58 AA; 6309 MW; DCFAC7137B6FC674 CRC64;
MFLAVDRYSG GNAYCPRPTP PWQKEITTFF TAKPKEPSGS SESGEGSSTQ ADVHSDQE
//
