ID B7Q3F7_IXOSC Unreviewed; 257 AA.
AC B7Q3F7;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Tubulin-specific chaperone B, putative {ECO:0000313|EMBL:EEC13379.1, ECO:0000313|EnsemblMetazoa:ISCW008984-PA};
GN Name=8035307 {ECO:0000313|EnsemblMetazoa:ISCW008984-PA};
GN ORFNames=IscW_ISCW008984 {ECO:0000313|EMBL:EEC13379.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC13379.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC13379.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW008984-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW008984-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TBCB family.
CC {ECO:0000256|ARBA:ARBA00025779}.
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DR EMBL; ABJB010921702; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS849458; EEC13379.1; -; Genomic_DNA.
DR RefSeq; XP_002411255.1; XM_002411210.1.
DR AlphaFoldDB; B7Q3F7; -.
DR STRING; 6945.B7Q3F7; -.
DR PaxDb; 6945-B7Q3F7; -.
DR EnsemblMetazoa; ISCW008984-RA; ISCW008984-PA; ISCW008984.
DR GeneID; 8035307; -.
DR KEGG; isc:IscW_ISCW008984; -.
DR VEuPathDB; VectorBase:ISCI008984; -.
DR VEuPathDB; VectorBase:ISCP_006270; -.
DR VEuPathDB; VectorBase:ISCW008984; -.
DR HOGENOM; CLU_067577_2_0_1; -.
DR InParanoid; B7Q3F7; -.
DR OMA; ERYFACR; -.
DR OrthoDB; 5485090at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005938; C:cell cortex; IBA:GO_Central.
DR GO; GO:0035371; C:microtubule plus-end; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0043014; F:alpha-tubulin binding; IEA:InterPro.
DR GO; GO:0051010; F:microtubule plus-end binding; IBA:GO_Central.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IBA:GO_Central.
DR GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IEA:InterPro.
DR GO; GO:0007021; P:tubulin complex assembly; IEA:InterPro.
DR CDD; cd01789; Ubl_TBCB; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR045172; TBCB_Ubl.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF14560; Ubiquitin_2; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 12..66
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 189..231
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT COILED 132..159
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 257 AA; 28881 MW; A846E9BF813A3479 CRC64;
MCERGDSIPS FVKLLVRTEG TGGYSLERKF PVTDTVRELK QKLELLTGAS SASMRLELRD
AEGDKLVQRL VEGGDDARLD SFPALRDGLT LHVSDPLLNV EEFRDVSKVA KVELSQEAYN
RRNNSMRAYL QKHGLGRFNE DAQERAKRLE EEKAQKQREV LKVIHVGNRC EVVGIAGQPR
RRGTVAFVGE VDFKPGVWVG VRYDLPLGKN DGSVAGKRYF ECRPKYGGFV KPIDLMIGDY
PLEDDCVDGD CDLDEEM
//
