ID B7Q5M8_IXOSC Unreviewed; 346 AA.
AC B7Q5M8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Cuticle protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=IscW_ISCW020942 {ECO:0000313|EMBL:EEC14150.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC14150.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC14150.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW020942-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW020942-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010175062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS862434; EEC14150.1; -; Genomic_DNA.
DR RefSeq; XP_002402093.1; XM_002402049.1.
DR AlphaFoldDB; B7Q5M8; -.
DR PaxDb; 6945-B7Q5M8; -.
DR EnsemblMetazoa; ISCW020942-RA; ISCW020942-PA; ISCW020942.
DR KEGG; isc:IscW_ISCW020942; -.
DR VEuPathDB; VectorBase:ISCI020942; -.
DR VEuPathDB; VectorBase:ISCP_006558; -.
DR VEuPathDB; VectorBase:ISCP_011089; -.
DR VEuPathDB; VectorBase:ISCP_027698; -.
DR VEuPathDB; VectorBase:ISCW020942; -.
DR HOGENOM; CLU_063315_0_0_1; -.
DR InParanoid; B7Q5M8; -.
DR OMA; INIDIQH; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0062129; C:chitin-based extracellular matrix; IBA:GO_Central.
DR GO; GO:0008010; F:structural constituent of chitin-based larval cuticle; IBA:GO_Central.
DR Gene3D; 3.10.50.10; -; 3.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR000618; Insect_cuticle.
DR PANTHER; PTHR10380:SF245; CONSTITUENT OF CUTICLE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR10380; CUTICLE PROTEIN; 1.
DR Pfam; PF00379; Chitin_bind_4; 3.
DR PRINTS; PR00947; CUTICLE.
DR PROSITE; PS51155; CHIT_BIND_RR_2; 3.
PE 4: Predicted;
KW Cuticle {ECO:0000256|PROSITE-ProRule:PRU00497};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..346
FT /note="Cuticle protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014568238"
FT REGION 38..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 37213 MW; 08FB93FDFC856894 CRC64;
MLFEALLISL LGLSMAQDHN DDSGVYAPYP YSFGYDTTDE SGTRLTQSET GDEDNVKRGS
YSYSDANGLY RVVNYIADKD GFRVTIDTNE PGTKTSAPAG VQINSQAPPQ PYHFNYDTTD
EYGTRMTREE TSDANNAKVG SYSYTDASGV ARTVKYVADE NGFRATVETN EPGTKSHVTG
DAEYISNAPD YVAPANPAPA RPVPPQPYSF GFDSTNENGT RITQQETGDE NNVKTGSYSY
TDPYGIQRTV KYVADAEGFH VTIETNEPGT KSSNPADAQI VSASGEAPAP VEVKASPVVV
KVAQQVPVVH AIQTPVSYTT AQRVAPIAVA LSRAPLTYTL DKSKSS
//
