ID B7Q6M7_IXOSC Unreviewed; 244 AA.
AC B7Q6M7;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Salivary sulfotransferase, putative {ECO:0000313|EMBL:EEC14499.1, ECO:0000313|EnsemblMetazoa:ISCW010544-PA};
DE EC=2.8.2.2 {ECO:0000313|EMBL:EEC14499.1};
GN ORFNames=IscW_ISCW010544 {ECO:0000313|EMBL:EEC14499.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC14499.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC14499.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW010544-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW010544-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771}.
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DR EMBL; ABJB010043103; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS868927; EEC14499.1; -; Genomic_DNA.
DR RefSeq; XP_002403169.1; XM_002403125.1.
DR AlphaFoldDB; B7Q6M7; -.
DR PaxDb; 6945-B7Q6M7; -.
DR EnsemblMetazoa; ISCW010544-RA; ISCW010544-PA; ISCW010544.
DR KEGG; isc:IscW_ISCW010544; -.
DR VEuPathDB; VectorBase:ISCI010544; -.
DR VEuPathDB; VectorBase:ISCP_036600; -.
DR VEuPathDB; VectorBase:ISCW010544; -.
DR HOGENOM; CLU_027239_2_1_1; -.
DR InParanoid; B7Q6M7; -.
DR OMA; RITRTHF; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004027; F:alcohol sulfotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF334; SULFOTRANSFERASE SSU-1; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EEC14499.1}.
FT DOMAIN 66..233
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 244 AA; 28179 MW; F0556C169198FE5C CRC64;
MLAHGFIFGL CKQLEAAANH HGGDPYLIMS SSRRPSPRCQ LVDGIPRSPY LDPTLVRQAL
KHRPEDGDVI LMSFPKSGTH WTQQILQLIL NRGESATNFT DFVRRTPILE NHGAKALENL
PKPRITRTHF QLLRANVNEK AKYVYVARNP WDACVSAYHM LKSVPKFGFQ DATFDDFFEA
FMRGDYGYGE YFDHVMCGYS HRNDPNVFFF TYEQLKEDSR GVILRLAYFL GEKYGRMLEK
MRNS
//
