ID B7Q6T6_IXOSC Unreviewed; 567 AA.
AC B7Q6T6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Peroxinectin, putative {ECO:0000313|EMBL:EEC14558.1};
DE EC=1.11.1.7 {ECO:0000313|EMBL:EEC14558.1};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW011405 {ECO:0000313|EMBL:EEC14558.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC14558.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel colony {ECO:0000313|EMBL:EEC14558.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS870214; EEC14558.1; -; Genomic_DNA.
DR RefSeq; XP_002412033.1; XM_002411988.1.
DR AlphaFoldDB; B7Q6T6; -.
DR PaxDb; 6945-B7Q6T6; -.
DR KEGG; isc:IscW_ISCW011405; -.
DR VEuPathDB; VectorBase:ISCI011405; -.
DR VEuPathDB; VectorBase:ISCP_004316; -.
DR VEuPathDB; VectorBase:ISCW011405; -.
DR HOGENOM; CLU_006087_5_2_1; -.
DR OMA; NGQENFG; -.
DR PhylomeDB; B7Q6T6; -.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0140825; F:lactoperoxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd09823; peroxinectin_like; 1.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR PANTHER; PTHR11475:SF106; CURLY SU; 1.
DR PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR PRINTS; PR00457; ANPEROXIDASE.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Oxidoreductase {ECO:0000313|EMBL:EEC14558.1};
KW Peroxidase {ECO:0000313|EMBL:EEC14558.1}.
FT BINDING 348
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC14558.1"
FT NON_TER 567
FT /evidence="ECO:0000313|EMBL:EEC14558.1"
SQ SEQUENCE 567 AA; 63758 MW; 572F30D7F45FE33B CRC64;
LTQLCNPAPT GCDFSYPFRY PDGSCNNQNH TDWGNAGSCM RKLLRPDYGD MVGEPRVASD
GGPLPPPRVV SYTVHPPLEA SSPKMTQLGV LFGQFITHDV SQILRSGTPT AVNDIGKPWQ
PNLVSCCNSP QRTSPECLPM DVEADDPFYG DKNRTCMPLL RATPCFLCKL GYRVQVNDKT
SYLDASQVYG VRKTETDTLR TFRHGLLRSR IKNGEELLQP SSKPEEDGCS VPSENQICFT
SGDGRVNFTP GLTVIQTLFL RQHNRIAKML RSINRRWNDE MLFQVAKRIV ESQIQQVVYG
EWLPTFAGRD AVENYDLVPL QSGFTTYDSA VDATMIDEFS SSAFRMGHSL VSGNFLRVGA
DNKQQVGQLR DWYLRPFDLY QNGLDDIMRG MLLTPMATFD RFGSADMNEY FFKEQGMNFG
LDIFSIDVQR GRDQGVRGYT DYVEFCGGVK INTFQDLYQK NLMSQETAEI FQSLYKNVSD
IDLYSGAISE YVVEGTIASA TVHCITLKLF QRIKWGDRFY FEHADQAGSF TSAQLDSLRN
TTFAKIICAN SRSITAVQRN PFVPEGP
//
