ID B7Q7L9_IXOSC Unreviewed; 253 AA.
AC B7Q7L9;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 78.
DE RecName: Full=Calmodulin-binding domain-containing protein {ECO:0000259|SMART:SM01053};
DE Flags: Fragment;
GN Name=8037079 {ECO:0000313|EnsemblMetazoa:ISCW011573-PA};
GN ORFNames=IscW_ISCW011573 {ECO:0000313|EMBL:EEC14841.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC14841.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC14841.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW011573-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW011573-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ABJB010656197; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS876526; EEC14841.1; -; Genomic_DNA.
DR RefSeq; XP_002412185.1; XM_002412140.1.
DR AlphaFoldDB; B7Q7L9; -.
DR STRING; 6945.B7Q7L9; -.
DR PaxDb; 6945-B7Q7L9; -.
DR EnsemblMetazoa; ISCW011573-RA; ISCW011573-PA; ISCW011573.
DR GeneID; 8037079; -.
DR KEGG; isc:IscW_ISCW011573; -.
DR VEuPathDB; VectorBase:ISCI011573; -.
DR VEuPathDB; VectorBase:ISCP_035635; -.
DR VEuPathDB; VectorBase:ISCW011573; -.
DR HOGENOM; CLU_1100780_0_0_1; -.
DR InParanoid; B7Q7L9; -.
DR OrthoDB; 4200919at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR004178; CaM-bd_dom.
DR InterPro; IPR036122; CaM-bd_dom_sf.
DR InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR10153:SF33; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN; 1.
DR Pfam; PF02888; CaMBD; 1.
DR SMART; SM01053; CaMBD; 1.
DR SUPFAM; SSF81327; Small-conductance potassium channel; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 31..107
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000259|SMART:SM01053"
FT REGION 153..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..208
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC14841.1"
SQ SEQUENCE 253 AA; 28036 MW; 4CCD3092DA7130E7 CRC64;
GAGCTALVVA VIARKLELTR AEKHVHNFMM DTQLTKRLKN AAANVLRETW LIYKNTRLVK
RVNPSKVRAH QRKFLLAIYS LRKVKMDQRK LMDNANTITD MAKTQNSVYE MVSDMNARQE
LFDERLASLE ERLVAIHEQL EALPDAVARC CHSSLSQPPV PSQSYPPGSL LPSQQQQLQQ
QQQVPPDCGG PYPAAVPGQP SYPPHPPPKH THLHPDDAAS LTSRPSWSSV NLSGGRLGVM
APPMVARSGS TEN
//
