ID B7QCN4_IXOSC Unreviewed; 359 AA.
AC B7QCN4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Glutamate carboxypeptidase, putative {ECO:0000313|EMBL:EEC16606.1, ECO:0000313|EnsemblMetazoa:ISCW022413-PA};
DE EC=3.4.17.21 {ECO:0000313|EMBL:EEC16606.1};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW022413 {ECO:0000313|EMBL:EEC16606.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC16606.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC16606.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW022413-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW022413-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010509800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010821340; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS908885; EEC16606.1; -; Genomic_DNA.
DR RefSeq; XP_002413298.1; XM_002413253.1.
DR AlphaFoldDB; B7QCN4; -.
DR MEROPS; M28.012; -.
DR PaxDb; 6945-B7QCN4; -.
DR EnsemblMetazoa; ISCW022413-RA; ISCW022413-PA; ISCW022413.
DR KEGG; isc:IscW_ISCW022413; -.
DR VEuPathDB; VectorBase:ISCI022413; -.
DR VEuPathDB; VectorBase:ISCP_003825; -.
DR VEuPathDB; VectorBase:ISCW022413; -.
DR HOGENOM; CLU_005688_4_2_1; -.
DR InParanoid; B7QCN4; -.
DR OMA; HTIAPIR; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 2.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 1: Evidence at protein level;
KW Carboxypeptidase {ECO:0000313|EMBL:EEC16606.1};
KW Hydrolase {ECO:0000313|EMBL:EEC16606.1};
KW Protease {ECO:0000313|EMBL:EEC16606.1};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7QCN4};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 103..187
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 280..358
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC16606.1"
FT NON_TER 359
FT /evidence="ECO:0000313|EMBL:EEC16606.1"
SQ SEQUENCE 359 AA; 39091 MW; 72AE884F71AFD89C CRC64;
QLLLNYRFLA AEPHVAGTQR EENVLANYIK EKFTEYGLDF VKIASYDVLL SYPNVSDPNT
VQVLNISSGE VFFDAATQED VIPGVNSDIG PAFLAYSPPN DVLGNLVYVN YGTNEDFDML
QQMGVDINGA VCLTRYGNGY RGQKVRNCAA RGGVGALLFL DPEQVAREGL DNVFPNSTWM
PDTAMQRGSL MSVGDPMTPG VPALRKCMPL KAKCLSRPIF FYSEDTNVCF SSMLGGPLAP
QSFVGGFNMT YRVGPFADEH ADKYVRLRVN NLFSVVTVNN VIGGIEGAVE PDRVVITGNH
RDAWGYGASS PSSGTAALLE LARVLGQLKS KNVRPRRTVL LCSWAAGEYG LIGSTEWVE
//
