ID B7QFF0_IXOSC Unreviewed; 198 AA.
AC B7QFF0;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Charged multivesicular body protein 1a {ECO:0000256|ARBA:ARBA00020509};
DE AltName: Full=Chromatin-modifying protein 1a {ECO:0000256|ARBA:ARBA00032184};
GN Name=8040448 {ECO:0000313|EnsemblMetazoa:ISCW013340-PA};
GN ORFNames=IscW_ISCW013340 {ECO:0000313|EMBL:EEC17572.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC17572.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC17572.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW013340-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW013340-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the SNF7 family.
CC {ECO:0000256|ARBA:ARBA00006190}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABJB010759400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS925401; EEC17572.1; -; Genomic_DNA.
DR RefSeq; XP_002414264.1; XM_002414219.1.
DR AlphaFoldDB; B7QFF0; -.
DR STRING; 6945.B7QFF0; -.
DR PaxDb; 6945-B7QFF0; -.
DR EnsemblMetazoa; ISCW013340-RA; ISCW013340-PA; ISCW013340.
DR KEGG; isc:IscW_ISCW013340; -.
DR VEuPathDB; VectorBase:ISCI013340; -.
DR VEuPathDB; VectorBase:ISCP_010076; -.
DR VEuPathDB; VectorBase:ISCW013340; -.
DR HOGENOM; CLU_080826_0_0_1; -.
DR InParanoid; B7QFF0; -.
DR OMA; MDPMKIA; -.
DR OrthoDB; 260657at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0000815; C:ESCRT III complex; IBA:GO_Central.
DR GO; GO:0005771; C:multivesicular body; IBA:GO_Central.
DR GO; GO:0032509; P:endosome transport via multivesicular body sorting pathway; IBA:GO_Central.
DR GO; GO:0045324; P:late endosome to vacuole transport; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IBA:GO_Central.
DR Gene3D; 6.10.140.1230; -; 1.
DR InterPro; IPR005024; Snf7_fam.
DR PANTHER; PTHR10476; CHARGED MULTIVESICULAR BODY PROTEIN; 1.
DR PANTHER; PTHR10476:SF17; CHARGED MULTIVESICULAR BODY PROTEIN 1A; 1.
DR Pfam; PF03357; Snf7; 1.
PE 1: Evidence at protein level;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7QFF0};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 170..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 198 AA; 21971 MW; 4E08E8EF192E1717 CRC64;
MDDMIFQLRF SCKQLERLSK RAEKDEKIQK AKIKKALQQG NVEGARIYAE NAIRKKNEGL
NYLRMASKVD AVSSKIKSAM AMKQVTKNMA GVVKALDKAI NSMDLQKVSA VMEKFEQQFE
DLDVRTAVLD DAMGTATTTT TPMAQVDQLI QQVAEESGLE MIDEVNKAEL APSDSIATTG
RPQAEEDALT KRLAALRE
//
