ID B7QJ38_IXOSC Unreviewed; 271 AA.
AC B7QJ38;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 08-NOV-2023, entry version 78.
DE SubName: Full=Protein sine oculis, putative {ECO:0000313|EMBL:EEC18860.1, ECO:0000313|EnsemblMetazoa:ISCW023235-PA};
GN ORFNames=IscW_ISCW023235 {ECO:0000313|EMBL:EEC18860.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC18860.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC18860.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW023235-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW023235-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR EMBL; ABJB010361401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010900035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS949314; EEC18860.1; -; Genomic_DNA.
DR AlphaFoldDB; B7QJ38; -.
DR STRING; 6945.B7QJ38; -.
DR PaxDb; 6945-B7QJ38; -.
DR EnsemblMetazoa; ISCW023235-RA; ISCW023235-PA; ISCW023235.
DR KEGG; isc:IscW_ISCW023235; -.
DR VEuPathDB; VectorBase:ISCI023235; -.
DR VEuPathDB; VectorBase:ISCP_036953; -.
DR VEuPathDB; VectorBase:ISCW023235; -.
DR HOGENOM; CLU_046914_4_2_1; -.
DR InParanoid; B7QJ38; -.
DR OMA; RDEMRNN; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005667; C:transcription regulator complex; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR031701; SIX1_SD.
DR PANTHER; PTHR10390:SF44; HOMEOBOX DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF16878; SIX1_SD; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 216..267
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 218..268
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 60..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 271 AA; 30675 MW; 7B7DC5105955A01C CRC64;
MDCRADIDDD DDSSSLVSQR HLLGRTSGHQ LINGVHADVG IDGDMRSLVL DSESTCAGLD
NGGLGGGGGG PRLTELRSSS SSSSSSPGNK AMVFSLEQVA CVCEALQQAK NLDRLARFLW
SLPPGDLLHA NEAVLRAQAA VAFHRGNYKE LYTILEGHNF NPRYHNELQQ MWYKAHYREA
EKIRGRQLGA VDKYRLRRKY PLPKTIWDGE DTVYCFKEKS RVALKECYKH NRYPTPDEKR
TLVNKTGLTF TQVSNWFKNR RQRDRTPHHR T
//
