ID B7QKB2_IXOSC Unreviewed; 275 AA.
AC B7QKB2;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE SubName: Full=Arylsulfatase B, putative {ECO:0000313|EMBL:EEC19284.1, ECO:0000313|EnsemblMetazoa:ISCW013931-PA};
DE EC=3.1.6.12 {ECO:0000313|EMBL:EEC19284.1};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW013931 {ECO:0000313|EMBL:EEC19284.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC19284.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC19284.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW013931-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW013931-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR EMBL; ABJB010189376; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010237242; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010282671; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010457879; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010508848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010719326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010722880; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010824521; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010922300; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010995775; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS958545; EEC19284.1; -; Genomic_DNA.
DR RefSeq; XP_002400856.1; XM_002400812.1.
DR AlphaFoldDB; B7QKB2; -.
DR STRING; 6945.B7QKB2; -.
DR PaxDb; 6945-B7QKB2; -.
DR EnsemblMetazoa; ISCW013931-RA; ISCW013931-PA; ISCW013931.
DR KEGG; isc:IscW_ISCW013931; -.
DR VEuPathDB; VectorBase:ISCI013931; -.
DR VEuPathDB; VectorBase:ISCP_016904; -.
DR VEuPathDB; VectorBase:ISCW013931; -.
DR HOGENOM; CLU_052891_0_0_1; -.
DR InParanoid; B7QKB2; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0003943; F:N-acetylgalactosamine-4-sulfatase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR047115; ARSB.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR10342; ARYLSULFATASE; 1.
DR PANTHER; PTHR10342:SF273; RE14504P; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EEC19284.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 1..98
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC19284.1"
SQ SEQUENCE 275 AA; 30921 MW; 6A881C93297F9959 CRC64;
AVYELDKSVG LVMEALNKRG MLKNSIIVFS TDNGGLPWGE EPNSGYNWPL RGAKFTLWEG
GVRGAAFVWS PLLSKSGRLS NQLMHITDWL PTLYSAADNI SALIVGRRKI VLGSYNEGMY
DLRMKAPGGS RTVDGLDRMM LSSRTGKVLK DFYNVRQLTV RPNWRNETVV RCDQYAPRDN
FVAASPPYYF DLEHDPCELN NLAASNMTEL KELIMKIEEY AKSMDVGDQT FLARGNQKVF
PSQEQPGHGF NVELRHGSWV SRSYLRGSVP SESQN
//
