ID B7QLU1_IXOSC Unreviewed; 761 AA.
AC B7QLU1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=O-linked N-acetylglucosamine transferase, OGT, putative {ECO:0000313|EMBL:EEC19813.1, ECO:0000313|EnsemblMetazoa:ISCW014790-PA};
GN ORFNames=IscW_ISCW014790 {ECO:0000313|EMBL:EEC19813.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC19813.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC19813.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW014790-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW014790-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010126216; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010401740; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010458405; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010492025; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010578448; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010879150; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010945865; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010967298; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010977112; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011016689; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS967721; EEC19813.1; -; Genomic_DNA.
DR RefSeq; XP_002416146.1; XM_002416101.1.
DR AlphaFoldDB; B7QLU1; -.
DR STRING; 6945.B7QLU1; -.
DR PaxDb; 6945-B7QLU1; -.
DR EnsemblMetazoa; ISCW014790-RA; ISCW014790-PA; ISCW014790.
DR KEGG; isc:IscW_ISCW014790; -.
DR VEuPathDB; VectorBase:ISCI014790; -.
DR VEuPathDB; VectorBase:ISCP_001056; -.
DR VEuPathDB; VectorBase:ISCW014790; -.
DR HOGENOM; CLU_011615_2_0_1; -.
DR InParanoid; B7QLU1; -.
DR OMA; VLYHRWD; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000030; F:mannosyltransferase activity; IBA:GO_Central.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IBA:GO_Central.
DR GO; GO:0035269; P:protein O-linked mannosylation; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44227; -; 1.
DR PANTHER; PTHR44227:SF3; PROTEIN O-MANNOSYL-TRANSFERASE TMTC4; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 4.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Transferase {ECO:0000313|EMBL:EEC19813.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 112..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 526..559
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 594..627
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 662..695
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 696..729
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 740..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 525..552
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 761 AA; 86601 MW; 7634088F4123AF54 CRC64;
MTQLFDHNRN ATGVKNGAVR GSDRNEGPHW DRALPVPPWA LRLGPCLVVA ASLACFANSV
SGDFVFDDSE AVVNNANVRP ETPLSRLLED DFWGTRLLAP SSHKSYRPLT TLTFKVLPTL
SFCHLPVTGF SIINCYLFSV TLKTNVYRAL FPVLLQGAPR ASLLCALLFA VHPVHTENVS
AVVGRADLLC ALFFVLSFLC FVHSCYTPCG EGGLQYDVRS SCLWLLGSAA LAVVSMLCKE
PGITVIVSIL YKLISQSGHW NKVVKVISLH LQVREMTCVM LKFNYVMLKF NFVFVGCRFY
NCHWWPYWLG HKLPPDLKGN AKFIHPAVIV GEQGQHSFKL VFWQIGISLI QSHICKTLYG
IKCLRFWKVS SEAVHFDMVI MMPRIRSCAF VTHQCRLLCM CLALMVVPFL PASNLFFRVG
FVVAERVLYL PSLGFCALVV VGAAHLAAWA PRHSKFNYVM LKFNFVFVGC RFYNCHWWPY
WLFSSADRYR YVASCVHDML TICEHSTIEI SGRVVTVCMK YYLQYVTAMN NLANILKDLD
QLSEARELLE RAIQIRPDFA AAWMNLGIVQ SSLGMQSEAE RSYRMAIQHR SKYPDCYYNL
GNLYLKQGRY EEAYRAWRNA TRQRPSHLSS WNNLVIMLDQ RGLLAEAERA ALQGLAQLGQ
EPSLHFNLAN TLGKAGKHRR SEHHFLRALA LSPDNPSYHT NLGVLYHRWK KFDKAEESYR
RALQLNPDLK SAQENLEMLL QQKRPQGTAA KPQDTKRNRR T
//
