ID B7QM38_IXOSC Unreviewed; 1179 AA.
AC B7QM38;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE RecName: Full=PHD-type domain-containing protein {ECO:0000259|PROSITE:PS50016};
GN ORFNames=IscW_ISCW023204 {ECO:0000313|EMBL:EEC19910.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC19910.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC19910.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW023204-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW023204-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABJB010145840; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010410037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010508200; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010514475; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010676530; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010733060; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010814561; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010885978; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010958627; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS968935; EEC19910.1; -; Genomic_DNA.
DR RefSeq; XP_002416243.1; XM_002416198.1.
DR AlphaFoldDB; B7QM38; -.
DR STRING; 6945.B7QM38; -.
DR PaxDb; 6945-B7QM38; -.
DR EnsemblMetazoa; ISCW023204-RA; ISCW023204-PA; ISCW023204.
DR KEGG; isc:IscW_ISCW023204; -.
DR VEuPathDB; VectorBase:ISCI023204; -.
DR VEuPathDB; VectorBase:ISCP_036742; -.
DR VEuPathDB; VectorBase:ISCW023204; -.
DR HOGENOM; CLU_273231_0_0_1; -.
DR InParanoid; B7QM38; -.
DR OMA; HREDMAQ; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15509; PHD1_KMT2C_like; 1.
DR CDD; cd15510; PHD2_KMT2C_like; 1.
DR CDD; cd15513; PHD5_KMT2C_like; 1.
DR CDD; cd15514; PHD6_KMT2C_like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 6.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR PANTHER; PTHR45888:SF6; HL01030P-RELATED; 1.
DR Pfam; PF00628; PHD; 4.
DR SMART; SM00249; PHD; 6.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 6.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 6.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 22..74
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 71..121
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 154..207
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 285..338
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 335..385
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 412..467
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 515..915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 953..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..747
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..768
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 780..806
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..845
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..899
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 957..989
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1150
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1179 AA; 126814 MW; 53597046E5CE619E CRC64;
MKALILLCPV HANKAVSYVG SQANCQSCEE MVSPSELLFC TLCGAHYHGF CLDPAVRVTT
STRVGWQCPD CKACQACRRP GDEARLLTCD ICDKGFHVYC VKPVVANVPK HGWKCQNCRV
CGDCGSRTPG SGPSSRWHMN FSVCDSCYQQ RNKGVACPLC GKAYRQFSHR EDMAQCTMCR
KYIHMECDSQ LANHQDADYV CPVCNNTRQQ ATGGKLAAKR RAKAVELRRK RGPKPKLKSY
FLGCNVPQGA TAAIPETKDL KQDDEPAMDN KMVLFSASDD FVLSQDLCAM CGSFGRAEEG
RLIACAQCGQ CYHPYCVNVK VTRMILKKGW RCLDCTVCEG CGQPHDESRL LLCDECDISY
HTYCLSPPLE NVPQGNWKCR WCVVCLQCGA TDPGFGSHWQ NNYTQCGPCA SKTSCPLCLL
KYQENDLVIQ CVQCERWMHG FCDQIACEED AEKCAEYGYN CPYCRPKDEL PPHLLKEYIE
PPPPAPVKAK PQPAQFYMDG VFLSESGMHQ IKALTIEQPK RQRARRPRVP SGGPPPTPTL
AGAFGAFRGR LSTEDSEDGS KDLPDMDVEP KMEVDEETKL TSEEVAKLDA ESELKKKRQR
KLQKLATEPS SEAALAALAG DGASQAPEAP ADVAAAGGPE KPKRRRRVKK KNPLEDSFPS
YLQEAFFGHD LLLTSRTEPT PEMPSEDEED SAPGRPEANM IVLEALQDPS EDAPSDSGAP
SPAARTGSKG VSPALQDEGT STPVKTGSDD EDLGLKDILP HDLPQDDELM DMLMNEGDDL
SKQGSGSRGV KDNDPLSGNN IDTVLLSPHF NLVDSMVSAG SGGPNDSVGS IGTSGAGMSP
LQQPGSSGAR PPPLMQNPLT PASSHSVGSP FSMPSPSPFP VDYGSPQLSE PPPSPWMDPE
AELPSSGGQK NILKWESDEA LGSGATISPV LYANLNCQNL RMEYPIGKGH QMMLGETSPA
GSLSPSAPSP TPSQLMGAAA QSPLSPAQAQ RSPGPVRVPP APVSPLIQVS RVRPPIDPSR
LPPSGSDPYA LPMAPSSSAG PLGVAERFLP PRPPPVGGLV GAPPRMLRPP EDGTRTTPPH
TPSPTGRGPL DPYAQMPGTP RPAPSDTSAY HQPYLRAQPG GPPLKVARPP PQADPYAAPP
GTPMPEPGQA RYSPQPVYGA PRVPQQAQVC DGRAPQSFS
//
