ID B7RZA8_9GAMM Unreviewed; 431 AA.
AC B7RZA8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:EEB78131.1};
GN ORFNames=GPB2148_756 {ECO:0000313|EMBL:EEB78131.1};
OS marine gamma proteobacterium HTCC2148.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=247634 {ECO:0000313|EMBL:EEB78131.1, ECO:0000313|Proteomes:UP000002793};
RN [1] {ECO:0000313|Proteomes:UP000002793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2148 {ECO:0000313|Proteomes:UP000002793};
RX PubMed=20472793; DOI=10.1128/jb.00511-10;
RA Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA Giovannoni S.J.;
RT "Genome sequences of strains HTCC2148 and HTCC2080, belonging to the
RT OM60/NOR5 clade of the Gammaproteobacteria.";
RL J. Bacteriol. 192:3842-3843(2010).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; DS999229; EEB78131.1; -; Genomic_DNA.
DR AlphaFoldDB; B7RZA8; -.
DR STRING; 247634.GPB2148_756; -.
DR eggNOG; COG0535; Bacteria.
DR HOGENOM; CLU_635853_0_0_6; -.
DR OrthoDB; 9792276at2; -.
DR Proteomes; UP000002793; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002793};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 70..297
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 431 AA; 48163 MW; AB8A7978FF296183 CRC64;
MNNNIPLTDV DAPVQEPEDQ LELASIHDFA TKLVQPGAKE ALEHYVRWQI AMRNATDADA
IDLDPSKVPD FAPISINLDL TTACNYACDH CVDLDILNTG IRFDHEKLLE SIKVMAERGM
KSVIVIGGGE PTLYPKFEET IRFMKDLKLQ IAIVSNGTGN DKIAKVADCM DKADWVRLSL
DSGTDATFQP MHNPRKDFDL EGICAKVPLI KDANPDVTVG FSYIVTWRGA EINDSAIVEN
LHEIAQATKL AKDNRFDYIS FKPFLTRDEV NNAEVIDIKA NAGLEDIINR IQAQVEEANT
LADDTFRVHQ STGLKAMLKR QTQSLAKQPQ QCHMQFFRQV LSPLGLYNCP VYRNQDHGRL
GDKNANAGVE AYDATRGVTA DLVKSFNATV ACEKVTCLYN DVNWWIEKLI ANPEELGKLS
WDEAAEPDYF L
//
