ID B7S0D8_9GAMM Unreviewed; 388 AA.
AC B7S0D8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Alcohol dehydrogenase, iron-containing superfamily {ECO:0000313|EMBL:EEB77881.1};
DE EC=1.1.1.1 {ECO:0000313|EMBL:EEB77881.1};
GN ORFNames=GPB2148_992 {ECO:0000313|EMBL:EEB77881.1};
OS marine gamma proteobacterium HTCC2148.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=247634 {ECO:0000313|EMBL:EEB77881.1, ECO:0000313|Proteomes:UP000002793};
RN [1] {ECO:0000313|Proteomes:UP000002793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2148 {ECO:0000313|Proteomes:UP000002793};
RX PubMed=20472793; DOI=10.1128/jb.00511-10;
RA Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA Giovannoni S.J.;
RT "Genome sequences of strains HTCC2148 and HTCC2080, belonging to the
RT OM60/NOR5 clade of the Gammaproteobacteria.";
RL J. Bacteriol. 192:3842-3843(2010).
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
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DR EMBL; DS999231; EEB77881.1; -; Genomic_DNA.
DR AlphaFoldDB; B7S0D8; -.
DR STRING; 247634.GPB2148_992; -.
DR eggNOG; COG1454; Bacteria.
DR HOGENOM; CLU_007207_0_0_6; -.
DR OrthoDB; 9815791at2; -.
DR Proteomes; UP000002793; Unassembled WGS sequence.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd08193; HVD; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR PROSITE; PS00913; ADH_IRON_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EEB77881.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002793}.
FT DOMAIN 11..375
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 388 AA; 40060 MW; D414FBB4D72D9859 CRC64;
MQGFEFNTVG KIINGFGSAL EVAGQLSRLR VEKPLLITDP GLMSIGLVQP VVEALAAKGL
NPVVFDQVRE DPPEATVLAA AELGRMQGVD GVIAVGGGSS MDVAKVAAVL IGSDQPLSAL
YGVDQVKGER LPLILVPTTA GTGSEVTPVA VITTGETTKA GVSSSVLLPD VAVLDAQLTL
GLPAIITAMT GVDAMVHAIE AYTSRHRKNP ISDNLARQAL TLLATNIRTA VRDGSNAVAR
EGMLLGACMA GQAFANAPVA AVHALAYPLG GHYHIPHGLS NSLVLPAVMD FNMSVAAGAY
AELAELVVPG LQVDGEEARA SALIAAMRQL IDDLELPATL AAAGVSAADL EMLAKDAMEQ
QRLLVNNPRE VSYEDALGIY QAAYGEYA
//
