ID   B7XHH7_ENTBH            Unreviewed;       915 AA.
AC   B7XHH7;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN   ORFNames=EBI_24862 {ECO:0000313|EMBL:EED44660.1};
OS   Enterocytozoon bieneusi (strain H348) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Enterocytozoonidae;
OC   Enterocytozoon.
OX   NCBI_TaxID=481877 {ECO:0000313|EMBL:EED44660.1, ECO:0000313|Proteomes:UP000001742};
RN   [1] {ECO:0000313|EMBL:EED44660.1, ECO:0000313|Proteomes:UP000001742}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H348 {ECO:0000313|EMBL:EED44660.1,
RC   ECO:0000313|Proteomes:UP000001742};
RX   PubMed=18060071; DOI=10.1371/journal.pone.0001277;
RA   Corradi N., Akiyoshi D.E., Morrison H.G., Feng X., Weiss L.M., Tzipori S.,
RA   Keeling P.J.;
RT   "Patterns of genome evolution among the microsporidian parasites
RT   Encephalitozoon cuniculi, Antonospora locustae and Enterocytozoon
RT   bieneusi.";
RL   PLoS ONE 2:E1277-E1277(2007).
RN   [2] {ECO:0000313|EMBL:EED44660.1, ECO:0000313|Proteomes:UP000001742}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H348 {ECO:0000313|EMBL:EED44660.1,
RC   ECO:0000313|Proteomes:UP000001742};
RX   PubMed=19132089; DOI=10.1371/journal.ppat.1000261;
RA   Akiyoshi D.E., Morrison H.G., Lei S., Feng X., Zhang Q., Corradi N.,
RA   Mayanja H., Tumwine J.K., Keeling P.J., Weiss L.M., Tzipori S.;
RT   "Genomic survey of the non-cultivatable opportunistic human pathogen,
RT   Enterocytozoon bieneusi.";
RL   PLoS Pathog. 5:E1000261-E1000261(2009).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EED44660.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ABGB01000014; EED44660.1; -; Genomic_DNA.
DR   RefSeq; XP_002649430.1; XM_002649384.1.
DR   AlphaFoldDB; B7XHH7; -.
DR   STRING; 481877.B7XHH7; -.
DR   VEuPathDB; MicrosporidiaDB:EBI_24862; -.
DR   HOGENOM; CLU_318069_0_0_1; -.
DR   InParanoid; B7XHH7; -.
DR   OMA; RMEIKIN; -.
DR   OrthoDB; 12619at2759; -.
DR   Proteomes; UP000001742; Unassembled WGS sequence.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   CDD; cd21206; CH_IQGAP; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR000593; RasGAP_C.
DR   PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF03836; RasGAP_C; 1.
DR   SMART; SM00033; CH; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   PROSITE; PS50021; CH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001742}.
FT   DOMAIN          97..201
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
SQ   SEQUENCE   915 AA;  106613 MW;  91D7EA4791F05563 CRC64;
     MADNKSSFIS SDSNELNHNQ SINDELVGHV KPELISQVTN IKIKQTLQNI SNNKFEILND
     TIQINKTTTT ISQFGSSNIS AMEMDEKRKN TATHAFLIKM AEAREWVNTF VPCATVIELL
     DNLPTGVYLA QIAKLCGHKC RVHERSIENF AYLEVENIYA FLQFAKNIGL SSNFLFETND
     LREGKNLKQV IYCLHATAML LKRKGIGPGI KKPTQSFTEE EMNMIDQHQT ETIDAFDNLE
     NELNKLDGIA QTTTNNYENQ NIMLNTDERD SIKRDSISRI QSCIDTLLFL NAFRNILYNN
     KINLISLKKF IFLMPCDQPE LIGTDIIEQF RCNFTLKTRI DNIYRNVRLL LSNQSILRGI
     SNKSMQKTED LSLFQKALYL FLIQYELIKN LITEKEEIPL ELIYPDSVIG DYHFTKLISL
     FNLKYINENN DIILLVQQHF RNSKMFKELV NLFNSKEELP NINPVEIYKE LYNLQIHDQK
     ALIETAMGEE KVRKEINSRC EIFKDYLEKI ITYFNNTNFP IYCNLFINKW EIFIEDIVLN
     SNNKKYAVLF KKIYNNTLDP NILDDFNDDI MFIFNKMSPL YEFITTYNIK VPNCLFKTED
     DINSALIQHL EYADNLKFNF TYDTINMLVF ILKKHKDRFK GVLRRMTEEV SVFNHKNETV
     NIVIDNSHMN YDDQNELYSG LSSIISETKK KLVLLIKNSK KRDIMSMLFS DKNINTDNID
     SDETGCYSSD FTNVNISTRE NLNNIKKSLI ADLKFLESEG ITFKRNKYNE ILDMIAKDIL
     KPENKDVELT GEIAELVYQQ GEALMSNLMR LEEYYNSFIA KYTTGYSSSI RLFVNKDKLL
     NQELESAEII INEIKPTFYQ FEIISNNKPI VTDHLYLTDI LKLKEEGNDK LEIGKVVKMD
     LKTILFLINS KYVVY
//