ID   B7ZQA4_XENLA            Unreviewed;       884 AA.
AC   B7ZQA4;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Nuclear factor of activated T-cell {ECO:0000313|EMBL:AAI69736.1};
GN   Name=nf-at {ECO:0000313|EMBL:AAI69736.1};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355 {ECO:0000313|EMBL:AAI69736.1};
RN   [1] {ECO:0000313|EMBL:AAI69736.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula {ECO:0000313|EMBL:AAI69736.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC169736; AAI69736.1; -; mRNA.
DR   AlphaFoldDB; B7ZQA4; -.
DR   IntAct; B7ZQA4; 1.
DR   STRING; 8355.B7ZQA4; -.
DR   PaxDb; 8355-B7ZQA4; -.
DR   OMA; RTRYANC; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd01178; IPT_NFAT; 1.
DR   CDD; cd07881; RHD-n_NFAT; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR008366; NFAT.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR032397; RHD_dimer.
DR   InterPro; IPR011539; RHD_DNA_bind_dom.
DR   InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR   PANTHER; PTHR12533; NFAT; 1.
DR   PANTHER; PTHR12533:SF6; NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3; 1.
DR   Pfam; PF16179; RHD_dimer; 1.
DR   Pfam; PF00554; RHD_DNA_bind; 1.
DR   PRINTS; PR01789; NUCFACTORATC.
DR   SMART; SM00429; IPT; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   PROSITE; PS50254; REL_2; 1.
PE   2: Evidence at transcript level;
KW   Activator {ECO:0000256|ARBA:ARBA00023159}.
SQ   SEQUENCE   884 AA;  97657 MW;  B92724A4FA745EB0 CRC64;
     MSAAHCGWED LDFRAIFGEE SLENHDSADI APDDCASFFI FSRDQANSSV SQPVCIPYNE
     HQMHSSTHSS CLQDYRNNDG SKEIPDYTYS SSVGTKSFEC PSIQITSISP SCHQDIETLE
     NAENNGSERD YMDRPLRDHL CLHLEPTFRD PSLSPSPGSS ISSRSWISDA SSCESLSHIY
     DDLDSELNEA AARFTLGSPL TSPSGSPREY CSVSPSPRQS PCHSPRNSIT DENWLSPRSA
     SKPPSRPTSP CGKRRHSSAD IFYSGLVSPH YSPATSPGPS PRGSITEDTW LSASPHPAPS
     LSLYPCWQET AIPLKTRKTS EDHSARLAGK TELNTEDLAC LSPIVDMPAD ETSCSQHLLV
     QDSSTDQFLS VPSHFTWNKH KSGHTPVFRT SSLPPLDWAL PSRYGQYELK VEVQPKTHHR
     AHYETEGSRG AVKAVTGSHP IVKLIGYTEK PVNVQIFIGT ADERYVKPHA FYQIHRITGK
     TVVTASQEIV ITNTKVLEIP LLPENNMTAS IDCAGILKLR NSDIELRKGE TDIGRKNTRV
     RLVFRAHIPQ TSGKVLSLQT ASIPIECSQR SAQELPQVEK YSVNSCSVNG GLELVITGSN
     FMPDSKVIFL EKGQDGCTHW EAEGKIVLKK CQMNNIVVEI PAYHNKSVAA EVQVQFYVCN
     GKRKRSQSQR FNYTPVLLKQ ENLEDGNLQE ATAVSVAKGR GISDLHIIHT NLLFQDQRSI
     CKTLKSLSPP GVGCPNQLTF TSSLKHEAPH ISNIQEPCTS SSPCTADPET MENYPDTIYS
     SPQKQSMPYQ GFSSDITILP SSSLTAMPHC GQPSSHTHDC RLRDNSLSPT ITHHRQNSTS
     SHPTDMSLGI KSELEDSDIN FQTKDLQDIT LDDVAEIIRR DMSH
//