ID B8AM88_ORYSI Unreviewed; 872 AA.
AC B8AM88;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
GN ORFNames=OsI_14033 {ECO:0000313|EMBL:EEC76398.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946 {ECO:0000313|EMBL:EEC76398.1, ECO:0000313|Proteomes:UP000007015};
RN [1] {ECO:0000313|EMBL:EEC76398.1, ECO:0000313|Proteomes:UP000007015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11 {ECO:0000313|Proteomes:UP000007015};
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J.,
RA Samudrala R., Wang J., Wong G.K., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrA/ParC subunit
CC family. {ECO:0000256|ARBA:ARBA00008263}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM000128; EEC76398.1; -; Genomic_DNA.
DR AlphaFoldDB; B8AM88; -.
DR STRING; 39946.B8AM88; -.
DR EnsemblPlants; BGIOSGA009580-TA; BGIOSGA009580-PA; BGIOSGA009580.
DR Gramene; BGIOSGA009580-TA; BGIOSGA009580-PA; BGIOSGA009580.
DR HOGENOM; CLU_002977_6_1_1; -.
DR OMA; THHWLLF; -.
DR Proteomes; UP000007015; Chromosome 3.
DR GO; GO:0016592; C:mediator complex; IEA:EnsemblPlants.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0034335; F:DNA negative supercoiling activity; IEA:EnsemblPlants.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00187; TOP4c; 1.
DR Gene3D; 3.30.1360.40; -; 1.
DR Gene3D; 2.120.10.90; DNA gyrase/topoisomerase IV, subunit A, C-terminal; 1.
DR Gene3D; 3.90.199.10; Topoisomerase II, domain 5; 1.
DR Gene3D; 1.10.268.10; Topoisomerase, domain 3; 1.
DR InterPro; IPR006691; GyrA/parC_rep.
DR InterPro; IPR035516; Gyrase/topoIV_suA_C.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR013758; Topo_IIA_A/C_ab.
DR InterPro; IPR013757; Topo_IIA_A_a_sf.
DR InterPro; IPR002205; Topo_IIA_dom_A.
DR PANTHER; PTHR43493:SF5; DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL; 1.
DR PANTHER; PTHR43493; DNA GYRASE/TOPOISOMERASE SUBUNIT A; 1.
DR Pfam; PF03989; DNA_gyraseA_C; 6.
DR Pfam; PF00521; DNA_topoisoIV; 1.
DR SMART; SM00434; TOP4c; 1.
DR SUPFAM; SSF101904; GyrA/ParC C-terminal domain-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000007015};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 1..448
FT /note="DNA topoisomerase type IIA"
FT /evidence="ECO:0000259|SMART:SM00434"
FT REGION 839..872
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..857
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 858..872
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 872 AA; 96711 MW; 51673B5FAE49569B CRC64;
MAYAMSVLLG RALPDVRDGL KPVHRRILYA MHEMGLASRR PFRKCARVVG EVLGKFHPHG
DSAVYETLVR MAQDFSMRYP LVQGHGNFGS IDADPPAAMR YTECRLDVGC FFFLDIDAIF
IIGQVDFVPN FDNSQKEPSL LPARVPSLLL NGSSGIAVGM ATNIPPHNLG ELVDVLSVMI
ENPEATLQEL LECMPGPDFP TGGTIVGNQG ILEAYKTGRG RVVMRGKTDI ETIDVKSKRS
AIIIKEVPYQ TNKSTLVERI AELVEEKVLE GISDIRDESD RSGMRVVIEL KRGADPAIVL
NNLYRHTALQ SSFSCNMVAI LDGQPKLMGL KEILQAFIDF RCSVIERRAR FKLSQALERK
HIVEGIVIGL DNLDSVIQII RGTSNHAMAR ESLIKEFGLS DKQAEALLDI TLRKLTSLER
KKFVDEAKSL SEEISKLNEL LSNKKLIFQG LVDGLDYLRA EINVVIRELK LMWSLFKLIL
QEATDLKNKF ATPRRSFIED SASTEVDDLD IIPNEEMLLI LSEKGYVKRM KPNTFNLQNR
GTIGKSVGKM RMNDNTSDFI VCQTHDHVLY FSDKGIVYSA RAYKIPECTR AATGTPLVQL
LSLSDGERIT SIVPVNEFGE DQYLVMLTVN GYIKKVPLNA FSAIRTSGII SIQLAPGDEL
KWVRRCGDDD LVALASQNGM VIVNTCNKLR ALGRKTRGVL AMKLKEGDKM ASMDIIPATS
HNMPETYSRV RDLSPPWLLF IADNGIGKRV PLNAFRQGNF NRVGLQGYKL PPDCSLAAVF
VVGFSLTDDG ESDEQVVLVS QSGTVNRIKV KDISIRSRSA RGVILMRLEH AGKIQSASLI
SAAEEEEEQD PESASLISEA EEPEKQDPEV SA
//
