ID B8B6X0_ORYSI Unreviewed; 843 AA.
AC B8B6X0;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=SUI1 domain-containing protein {ECO:0000259|PROSITE:PS50296};
GN ORFNames=OsI_26284 {ECO:0000313|EMBL:EEC82174.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946 {ECO:0000313|EMBL:EEC82174.1, ECO:0000313|Proteomes:UP000007015};
RN [1] {ECO:0000313|EMBL:EEC82174.1, ECO:0000313|Proteomes:UP000007015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11 {ECO:0000313|Proteomes:UP000007015};
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J.,
RA Samudrala R., Wang J., Wong G.K., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Probably involved in translation.
CC {ECO:0000256|ARBA:ARBA00003130}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SUI1 family.
CC {ECO:0000256|ARBA:ARBA00005422}.
CC -!- SIMILARITY: Belongs to the tyrosyl-DNA phosphodiesterase family.
CC {ECO:0000256|ARBA:ARBA00010205}.
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DR EMBL; CM000132; EEC82174.1; -; Genomic_DNA.
DR AlphaFoldDB; B8B6X0; -.
DR STRING; 39946.B8B6X0; -.
DR EnsemblPlants; BGIOSGA024189-TA; BGIOSGA024189-PA; BGIOSGA024189.
DR Gramene; BGIOSGA024189-TA; BGIOSGA024189-PA; BGIOSGA024189.
DR HOGENOM; CLU_010413_1_0_1; -.
DR OMA; PLIKECW; -.
DR Proteomes; UP000007015; Chromosome 7.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0017005; F:3'-tyrosyl-DNA phosphodiesterase activity; IEA:EnsemblPlants.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd11566; eIF1_SUI1; 1.
DR CDD; cd22671; FHA_APTX-like; 1.
DR CDD; cd09122; PLDc_Tdp1_1; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR Gene3D; 3.30.780.10; SUI1-like domain; 1.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR InterPro; IPR005874; SUI1_euk.
DR InterPro; IPR010347; Tdp1.
DR NCBIfam; TIGR01160; SUI1_MOF2; 1.
DR PANTHER; PTHR12415; TYROSYL-DNA PHOSPHODIESTERASE 1; 1.
DR PANTHER; PTHR12415:SF0; TYROSYL-DNA PHOSPHODIESTERASE 1; 1.
DR Pfam; PF01253; SUI1; 1.
DR Pfam; PF06087; Tyr-DNA_phospho; 1.
DR SUPFAM; SSF55159; eIF1-like; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007015}.
FT DOMAIN 761..831
FT /note="SUI1"
FT /evidence="ECO:0000259|PROSITE:PS50296"
FT REGION 669..709
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..690
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 302
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-1"
FT ACT_SITE 531
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-1"
FT BINDING 304
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-2"
FT BINDING 533
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-2"
FT SITE 554
FT /note="Interaction with DNA"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-3"
SQ SEQUENCE 843 AA; 94113 MW; 2CD81EC4F06A53C3 CRC64;
MASSSRVRVG NLVPLNEGNA SSSNGSVSSI PIYLGANVVG RNHLVVVDKR VSRKHLSLHA
SADGSIEAVV EGPNPIIVRS EGQRRKVCAQ ERVKIAHDDV LELIPGEYFV KYLNVGDNHK
SSTSMGSSDF KKGKRLCEDD TVVIKRNRQI MEDEALARSL QKSFAEESST ISGLGCDQML
SSLDSAGSSE RNNERIHSVD YLKDVLSLTF RLMRVQGLPS WTNTSSVTIQ DVIQGEVLLA
VLSNYMVDME WLLTACPSLR KVRHVLVIHG EDGASVELLK KVKPANWILH KPPLPISFGT
HHSKAMLLVY PQGIRVVVHT ANLIHVDWNN KTQGLWMQDF PWKDAKDVNR IVSFENDLVD
YLSAIKWPEF RVNLPVVGDV NINAAFFRKF DYKSSLVRLI GSVPGYHVGP NIKKWGHMKL
RSVLEGCTFE QQFCKAPMIY QFSSLGSLDE KWMSEFACSL SAGKSDNGSP LGIGKPLIVW
PTVEDVRTSI EGYAAGSCIP SPQKNVEKDF LRKYWARWKA DHVGRCRAMP HIKTFTRYNG
QDIAWFLLTS ANLSKAAWGA LQKNNTQLMI RSYELGVLFL PKTHQSVPQF SCTGKNNSNL
NNLAPGKEIK TKLVTLCWKS DEEKEQSTEI IRLPVPYQLP PKPYGTEDDP WSWDKRYTKK
DVYGSVWPRH GGIQAKKRES TKDTRLAEAE RPPSRSISSG RVLGRSLPSS TSSSQVLGVA
CHFHQQSFMS DLDIQIPTAF DPFAEANAGD SGAAAGSKDY VHVRIQQRNG RKSLTTVQGL
KKEFSYNKIL KDLKKEFCCN GTVVQDPELG QVIQLQGDQR KNVSNFLVQA GIVKKEHIKI
HGF
//
