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Database: UniProt
Entry: B8BNR5_ORYSI
LinkDB: B8BNR5_ORYSI
Original site: B8BNR5_ORYSI 
ID   B8BNR5_ORYSI            Unreviewed;       993 AA.
AC   B8BNR5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   31-JUL-2019, entry version 66.
DE   RecName: Full=Urease domain-containing protein {ECO:0000259|PROSITE:PS51368};
GN   ORFNames=OsI_37894 {ECO:0000313|EMBL:EEC69053.1};
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946 {ECO:0000313|EMBL:EEC69053.1, ECO:0000313|Proteomes:UP000007015};
RN   [1] {ECO:0000313|EMBL:EEC69053.1, ECO:0000313|Proteomes:UP000007015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11 {ECO:0000313|Proteomes:UP000007015};
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H.,
RA   Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J.,
RA   Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X.,
RA   Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y.,
RA   Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J.,
RA   Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y.,
RA   Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y.,
RA   Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z.,
RA   Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T.,
RA   Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N.,
RA   Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA   Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA   Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J.,
RA   Samudrala R., Wang J., Wong G.K., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- COFACTOR:
CC       Name=Ni cation; Xref=ChEBI:CHEBI:25516;
CC         Evidence={ECO:0000256|PIRSR:PIRSR611612-51};
CC       Note=Binds 2 nickel ions per subunit.
CC       {ECO:0000256|PIRSR:PIRSR611612-51};
CC   -!- PTM: Carbamylation allows a single lysine to coordinate two nickel
CC       ions. {ECO:0000256|PIRSR:PIRSR611612-50}.
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DR   EMBL; CM000137; EEC69053.1; -; Genomic_DNA.
DR   MEROPS; M38.982; -.
DR   PRIDE; B8BNR5; -.
DR   EnsemblPlants; BGIOSGA036417-TA; BGIOSGA036417-PA; BGIOSGA036417.
DR   Gramene; BGIOSGA036417-TA; BGIOSGA036417-PA; BGIOSGA036417.
DR   eggNOG; ENOG410IGM6; Eukaryota.
DR   eggNOG; ENOG410JX8F; Eukaryota.
DR   eggNOG; COG0804; LUCA.
DR   eggNOG; COG0831; LUCA.
DR   eggNOG; COG0832; LUCA.
DR   HOGENOM; HOG000075064; -.
DR   OMA; GFDSHIH; -.
DR   Proteomes; UP000007015; Chromosome 12.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:EnsemblPlants.
DR   GO; GO:0043419; P:urea catabolic process; IEA:InterPro.
DR   CDD; cd00375; Urease_alpha; 1.
DR   CDD; cd00407; Urease_beta; 1.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   Gene3D; 2.30.40.10; -; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   HAMAP; MF_01953; Urease_alpha; 1.
DR   HAMAP; MF_01954; Urease_beta; 1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   InterPro; IPR011612; Urease_alpha_N_dom.
DR   InterPro; IPR017950; Urease_AS.
DR   InterPro; IPR005848; Urease_asu.
DR   InterPro; IPR017951; Urease_asu_c.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   InterPro; IPR040881; Urease_linker.
DR   InterPro; IPR029754; Urease_Ni-bd.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   Pfam; PF00449; Urease_alpha; 1.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   Pfam; PF18473; Urease_linker; 1.
DR   PRINTS; PR01752; UREASE.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF51338; SSF51338; 2.
DR   SUPFAM; SSF51556; SSF51556; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR01792; urease_alph; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
DR   PROSITE; PS01120; UREASE_1; 1.
DR   PROSITE; PS00145; UREASE_2; 1.
DR   PROSITE; PS51368; UREASE_3; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007015};
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00700};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR611612-51};
KW   Nickel {ECO:0000256|PIRSR:PIRSR611612-51};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007015}.
FT   DOMAIN      533    993       Urease. {ECO:0000259|PROSITE:PS51368}.
FT   REGION        1    104       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     60     82       Basic. {ECO:0000256|SAM:MobiDB-lite}.
FT   ACT_SITE    724    724       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR611612-52, ECO:0000256|PROSITE-
FT                                ProRule:PRU00700}.
FT   METAL       538    538       Nickel 1; via tele nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       540    540       Nickel 1; via tele nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       621    621       Nickel 1; via carbamate group.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       621    621       Nickel 2; via carbamate group.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       650    650       Nickel 2; via pros nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       676    676       Nickel 2; via tele nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR611612-51}.
FT   METAL       764    764       Nickel 1. {ECO:0000256|PIRSR:PIRSR611612-
FT                                51}.
FT   BINDING     623    623       Substrate. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00700}.
FT   MOD_RES     621    621       N6-carboxylysine. {ECO:0000256|PIRSR:
FT                                PIRSR611612-50}.
SQ   SEQUENCE   993 AA;  106304 MW;  7B115303A18C4CB4 CRC64;
     MAARGPEMGE SDPHAAAVLR DGDGSGGRRC SATAERGEKA EVALLSDGDG GGGGGGGGAA
     KGRRRRRQKR GASRRGRRWR RSKGKAAAAE VDGAAAAQKR EEFSPSVRPA NATYIYRISP
     PEFAIPIGDH SNRMKLVQRE AEKLALHNAG FLAQKRLARG LRLNYTEAVA LIAAQILEFV
     RDGDRTVTDL MDLGKQLLGR RQVLPAVPHL LETVQVEGTF MDGTKLITVH DPISSDDGNL
     ELALHGSFLP VPSLEKFSSV GVDDFPGEVR FCSGHIVLNL HRRALTLKVV NKADRPIQIG
     SHYHFIEANP YLVFDRQRAY GMRLNIPAGT AVRFEPGDAK TVTLVSIGGR KVIRGGNGIA
     DGAVNRSQLN EVMEKVIANG FGHEDYPDSS EGIIGDGTHD YSVDHEKYAS MYGPTTGDKI
     RLGDTDLFAE IEKDYAIYGD ECIFGGGKVL RDGMGQSAGY PASDCLDTVV TNAVVIDYTG
     IYKADIGING GLIVAIGKAG NPDVMDMDGV NEEMIVGVNT EVIAAEGMIV TAGGIDCHVH
     FICPQLAEEA IASGITTLVG GGTGPAHGTC ATTCTPSPSH MKLMLQSTDE LPINMGFTGK
     GNTTKPDGLA EIIKAGAMGL KLHEDWGSTP AAIDNCLSVA EAFDIQVNIH TDTLNESGCV
     EHTIAAFKDR TIHTYHSEGA GGGHAPDIIK VCGVKNVLPS STNPTRPFTL NTVDEHLDML
     MVCHHLDRNI PEDVAFAESR IRAETIAAED ILHDMGAISI ISSDSQAMGR IGERLFINCP
     NNVRVPCKCE VITRTWQTAN KMKRQRGRLP ISSSPDAAED NDNFRIRRYI AKYTINPAIV
     NGFSDFVGSV EVGKLADLVI WKPSFFGAKP EMVIKGGAIA CANMGDPNAS IPTPEPVMMR
     PMFGAFGGAG SANSIAFVSK AAKEAGVAVQ YKLGKRVEAV GRVRGLTKLN MKLNDALPKI
     DVDPETYTVT ADGEVLRCQP TPTVPLSRNY FLF
//
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