ID B8BZN9_THAPS Unreviewed; 957 AA.
AC B8BZN9;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Ribonuclease II/R domain-containing protein {ECO:0000259|SMART:SM00955};
GN ORFNames=THAPSDRAFT_4574 {ECO:0000313|EMBL:EED92915.1};
OS Thalassiosira pseudonana (Marine diatom) (Cyclotella nana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=35128 {ECO:0000313|EMBL:EED92915.1, ECO:0000313|Proteomes:UP000001449};
RN [1] {ECO:0000313|EMBL:EED92915.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED92915.1};
RX PubMed=15459382; DOI=10.1126/science.1101156;
RA Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D.,
RA Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M., Brzezinski M.A.,
RA Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S., Detter J.C.,
RA Glavina T., Goodstein D., Hadi M.Z., Hellsten U., Hildebrand M.,
RA Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N., Lau W.W., Lane T.W.,
RA Larimer F.W., Lippmeier J.C., Lucas S., Medina M., Montsant A., Obornik M.,
RA Parker M.S., Palenik B., Pazour G.J., Richardson P.M., Rynearson T.A.,
RA Saito M.A., Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A.,
RA Wilkerson F.P., Rokhsar D.S.;
RT "The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and
RT metabolism.";
RL Science 306:79-86(2004).
RN [2] {ECO:0000313|EMBL:EED92915.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED92915.1};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000256|ARBA:ARBA00004229}.
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DR EMBL; CM000641; EED92915.1; -; Genomic_DNA.
DR RefSeq; XP_002289378.1; XM_002289342.1.
DR AlphaFoldDB; B8BZN9; -.
DR STRING; 35128.B8BZN9; -.
DR PaxDb; 35128-Thaps4574; -.
DR EnsemblProtists; EED92915; EED92915; THAPSDRAFT_4574.
DR GeneID; 7448816; -.
DR KEGG; tps:THAPSDRAFT_4574; -.
DR eggNOG; ENOG502S7A3; Eukaryota.
DR HOGENOM; CLU_308501_0_0_1; -.
DR InParanoid; B8BZN9; -.
DR OMA; WEVLIHI; -.
DR Proteomes; UP000001449; Chromosome 4.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000932; C:P-body; IBA:GO_Central.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006402; P:mRNA catabolic process; IBA:GO_Central.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR001900; RNase_II/R.
DR PANTHER; PTHR23355:SF42; EXORIBONUCLEASE II, MITOCHONDRIAL; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF00773; RNB; 1.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001449};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 541..834
FT /note="Ribonuclease II/R"
FT /evidence="ECO:0000259|SMART:SM00955"
FT REGION 388..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 862..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 862..876
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 957 AA; 105719 MW; 5B3622DD00AC0267 CRC64;
MTTTHITDNV SIQKLNVAEC RRRRSQRIQC TSTTSLLVMP TMMMALHALP LLMVASFQYQ
GFTGVHRMRC CHRRFGGLGC TSLAHPSSRL ARDHTSSVLM SSYTDGYTDE VVQTLKRYGF
GSRVVSLTNY DLSTNPIPSE IYEGGDWNLC LIVGLKPPSS KTSDDGNMKP PLLDVILMDD
DGSLQERKVV DIGQITTLWN DFHEAYPNFT AKAMPETLQS ALVNAIGSLK NNIFPIEKAM
QNLYNSRIAN RSRPPSQQRY TLTKKQIPKI ASQCSNPPQL EELLRNLFKV GEDRLSRLVD
SALATDYLYT DFCRDGDNER LMRRMVAAQV LTEDAVLGGR FKRRSCQFVG AQYSFTGDDE
DIEVEQVTLV NGGWIAVDPS IKSRTEGRKF ASLSQDDLPQ VDTKKSDTKS PRVLTAADER
IAHRLECLAM GDIWNDVSDR DDEERALELD VREALSSMDL PLTSEGATNA LIRIGRWSQS
SEDNKRKKVF EPWSPAILEA ARALAMRESR RREHLAKICV TAKNNKTASQ SAPSSDDLEG
RANLCSLPCV CIDAKRASFR DDSVGIRLRS STGRKVNKAA SKWEVLIHIA DVSDLYFGQE
FRGGEDLSTD VLRRAAERRG QSRYDLPLGP LHLLPPVALE ALALATNVDG LPNRCVTLWA
YIDERDGKLL DAGLERTIIS SPKALSFAEA TSLLECNIDD TPQSLTNAKS IISVAERNLS
LWNRRHRQRN EAARKRESRL ATRELVASEL KAAGGQSRDD GVGGSFQRSR GHRLVDSSLD
LYAYAVGTMM KRANQPIPRA AGSGADRGGR LATAPLRRYI DGLAQRQALS VLCDYGSPLT
SDECHKAAKA VARATDNIAN LRSSKNRRDD SPRDRQSSGR QVSALHTLNR YLASTGGGQY
REVKAISSGK NNECVIVGAG ATGRVIGVSG TLKGGEKLLV EIIELDPERG VLDVRIV
//
