ID B8CCH9_THAPS Unreviewed; 867 AA.
AC B8CCH9;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=TFIIB-type domain-containing protein {ECO:0000259|PROSITE:PS51134};
GN ORFNames=THAPSDRAFT_24867 {ECO:0000313|EMBL:EED88956.1};
OS Thalassiosira pseudonana (Marine diatom) (Cyclotella nana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=35128 {ECO:0000313|EMBL:EED88956.1, ECO:0000313|Proteomes:UP000001449};
RN [1] {ECO:0000313|EMBL:EED88956.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED88956.1};
RX PubMed=15459382; DOI=10.1126/science.1101156;
RA Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D.,
RA Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M., Brzezinski M.A.,
RA Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S., Detter J.C.,
RA Glavina T., Goodstein D., Hadi M.Z., Hellsten U., Hildebrand M.,
RA Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N., Lau W.W., Lane T.W.,
RA Larimer F.W., Lippmeier J.C., Lucas S., Medina M., Montsant A., Obornik M.,
RA Parker M.S., Palenik B., Pazour G.J., Richardson P.M., Rynearson T.A.,
RA Saito M.A., Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A.,
RA Wilkerson F.P., Rokhsar D.S.;
RT "The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and
RT metabolism.";
RL Science 306:79-86(2004).
RN [2] {ECO:0000313|EMBL:EED88956.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED88956.1};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
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DR EMBL; CM000649; EED88956.1; -; Genomic_DNA.
DR RefSeq; XP_002293947.1; XM_002293911.1.
DR AlphaFoldDB; B8CCH9; -.
DR STRING; 35128.B8CCH9; -.
DR PaxDb; 35128-Thaps24867; -.
DR EnsemblProtists; EED88956; EED88956; THAPSDRAFT_24867.
DR GeneID; 7452693; -.
DR KEGG; tps:THAPSDRAFT_24867; -.
DR eggNOG; ENOG502SS10; Eukaryota.
DR HOGENOM; CLU_330790_0_0_1; -.
DR InParanoid; B8CCH9; -.
DR Proteomes; UP000001449; Chromosome 14.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000126; C:transcription factor TFIIIB complex; IBA:GO_Central.
DR GO; GO:0097550; C:transcription preinitiation complex; IBA:GO_Central.
DR GO; GO:0000995; F:RNA polymerase III general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0001006; F:RNA polymerase III type 3 promoter sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IBA:GO_Central.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IBA:GO_Central.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR Gene3D; 1.10.472.170; -; 1.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR013137; Znf_TFIIB.
DR PANTHER; PTHR11618:SF13; TRANSCRIPTION INITIATION FACTOR IIB; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR PRINTS; PR00685; TIFACTORIIB.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Reference proteome {ECO:0000313|Proteomes:UP000001449};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00469}.
FT DOMAIN 57..90
FT /note="TFIIB-type"
FT /evidence="ECO:0000259|PROSITE:PS51134"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..33
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 867 AA; 94457 MW; DD2DD8E24EE6326B CRC64;
MYNTASSSAS SSSSQMHHQK IHTSHRHHHH LHESIPQHSP PNDPNYHYHT PYTSSASSHP
CPYCSAPSTS FHCDASSGDL VCTSCGAVLD EHLRDEHAEW REYNNNNNDA ADKNVASKAR
CGGGDGSLVD EEKYVGGLMP TLLSNVPYSG GVARGTMEDR QTMSMLRKRL KRSHAIIEHM
VERDQKRRYE DVLLEGRARE AKLERGEEHD VVMQDDSCGN DDHRSLTVGG DYEALIAQRR
LKDDSTHRED ARQFTALKDK KWSIADAIVL HGSLDEVQHW VPRTTATTDS TYNDESTWSH
STLERERSTL TKKLDANTRS SLHKLYIAFE LLDKSCQKLE LNGVGNATFR EAMGWLMKYA
TKKDGLRVKG ISSGLGTGNN NIGGGGEDAQ PRRLLLSLLP FYHEIMSQSS TSKSTTTSTI
SLKTDLHRIK QYASLGAAII YLSAKRTGVG RTLAEVCSSF GTFSIVSGTN DESIARVDRG
GGGEEPLVRP KYCSRAMQEL RTVLPEVVSS AGSEVALPSV SQSSSPVKRE SDGDTEMKPA
AVSSSSVNVK REPVVSLGSR VALKLPECLA RVGSSSSTST EASSLSTKNN GMNSCVSSLP
TTEKAALVDL TSRMARSLNL PPFATAAAIA VAVQCARNNC ASSSSNGCVL SKPQRQVNKS
PLFITRKRSN SCQRGKGRNT SNRNSCAQKQ SPDVVAAASL LLVCMAGGKM QHLARQALSE
GSKNDQSGLI GDKLPSATVT NPLDELEDDV SSLKQTMFTN TATGSSVSTN HQQSGNGERE
ATASWSSWNQ QPPWHREVSQ LEQCTGLPSK TVVSYYSNAM HPRRSYFLGV AKKRLEEERD
GVDSRRGYFL RNIVAAVPLM SLRGLSI
//
