ID B8CDA4_THAPS Unreviewed; 1284 AA.
AC B8CDA4;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=Smr domain-containing protein {ECO:0000259|PROSITE:PS50828};
GN ORFNames=THAPSDRAFT_10136 {ECO:0000313|EMBL:EED88433.1};
OS Thalassiosira pseudonana (Marine diatom) (Cyclotella nana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=35128 {ECO:0000313|EMBL:EED88433.1, ECO:0000313|Proteomes:UP000001449};
RN [1] {ECO:0000313|EMBL:EED88433.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED88433.1};
RX PubMed=15459382; DOI=10.1126/science.1101156;
RA Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D.,
RA Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M., Brzezinski M.A.,
RA Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S., Detter J.C.,
RA Glavina T., Goodstein D., Hadi M.Z., Hellsten U., Hildebrand M.,
RA Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N., Lau W.W., Lane T.W.,
RA Larimer F.W., Lippmeier J.C., Lucas S., Medina M., Montsant A., Obornik M.,
RA Parker M.S., Palenik B., Pazour G.J., Richardson P.M., Rynearson T.A.,
RA Saito M.A., Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A.,
RA Wilkerson F.P., Rokhsar D.S.;
RT "The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and
RT metabolism.";
RL Science 306:79-86(2004).
RN [2] {ECO:0000313|EMBL:EED88433.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED88433.1};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
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DR EMBL; CM000650; EED88433.1; -; Genomic_DNA.
DR RefSeq; XP_002294078.1; XM_002294042.1.
DR STRING; 35128.B8CDA4; -.
DR PaxDb; 35128-Thaps10136; -.
DR EnsemblProtists; EED88433; EED88433; THAPSDRAFT_10136.
DR GeneID; 7451887; -.
DR KEGG; tps:THAPSDRAFT_10136; -.
DR eggNOG; ENOG502QRQR; Eukaryota.
DR HOGENOM; CLU_262875_0_0_1; -.
DR InParanoid; B8CDA4; -.
DR OMA; PGMIGES; -.
DR Proteomes; UP000001449; Chromosome 15.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.1370.110; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002625; Smr_dom.
DR InterPro; IPR036063; Smr_dom_sf.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF14; DNA MISMATCH REPAIR PROTEIN MUTS, TYPE 2; 1.
DR Pfam; PF00488; MutS_V; 1.
DR Pfam; PF01713; Smr; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
DR PROSITE; PS50828; SMR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001449}.
FT DOMAIN 1232..1279
FT /note="Smr"
FT /evidence="ECO:0000259|PROSITE:PS50828"
FT REGION 207..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1150..1169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 967..1041
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 207..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1284 AA; 142928 MW; C1AD4AFC5BC779A7 CRC64;
MHPETAFFHD EKRNHVKSLD DYYFIGGDTD VTATDKLTRI SLSDRAKEQD RRRRRKIIAA
LILVAFAEAT ECAADFMSVR VVSYLFVSST SLCRVPGRRK TTLTGTTPAT FEEDIKPSES
ALNTGNALHQ VELLWGARLQ HFSTPSDIVR LRMKALTSNY RFGDELMMDD DYAESLLQTY
TMIVSPVALL LVLRTSDAFQ FHRYSTPSSH RHTISPPPQH HPWQLCSTTQ NDDTQQSEAP
SSTFYDESTY RQRDSRAGED GYSILRRPVT FDADIDPTFD APRSLDEREE ERMNDANRNW
YEDKVAKGGG SGGYGKGSVV GAGILGEYAN TDLFKSNGDD DEKKMSSSSN KHQRQREEDQ
HLDMHQRTLD TLDYPLVLRA LANECGTVPG KEIVLDSLMK SGDASKRSKL TRKKKSSTDA
SDLDGDILTM PLTATSVEGV HRRFGALQEM QRLMEGRVSG WITSSRSQQS SDSNKKKRPQ
RKPLGAPPIE GYSFDFQPIF EIVDEGKVLE GPEILEVTTM LEIAMDVLDW RYALKEFNEE
IDNEADSDLK QEPFVELVSL TDSIEIDDEL FDLLTNAFDD EGRLSGTTFP FIGVLRAKVR
TFKRDILASI DSLLAMPSMK NKLAVESGGA LTMEINGRLV IPVQQKYQNI GIVHDASRSG
KTTYVEPTEI VGPTNELRQA EAELRSEEAR VWRQLTETIV KHRAEIERNV ASIGQLDVVI
GRVKLGKKLN GVVPTVREEG VVSVKDARHP ILLLRELEGV VGSDVEIGID GNQGLILTGP
NSGGKTVILK LLGLYAFMVR DGIPVPSKAY EPARVDFFTP ILADIGDLQS VDGDLSTFSG
HMLVCREVLN NAQENALVLM DELGSGTDPN QGVAIAQALL EALLDRGCRV AITTHYMDLK
QLASTDDRFA VAGMQFVGGR PTYKLIPGMI GESFALAVAE RLKLPQSVIQ RANELLDTET
RTMGELISSL EDQKLLVDQK QEELKKREFE MLELKAEMKR QQERLEAKQI NARREEAAKF
AAKLEEKERL LEDILEKLKG SGASKKVVAD SWTDIRIIKR EALSDAENVP GVMQRLKQQQ
GQVGDDELVP ISEMKGVNKV NIDDKVIVCK KGAFYGKEGV VKEVGKKISV AVGGVSVRLT
TKEISFLPSA GGVQKAKDPE EQQSSRAKRD MEYLTDEEVF VDVSSTATAI DKGVSMRMDA
NTVNCIGKNF EESKRKCIDA FSKATMSNRS VVFILHGHGT GVLKKKIRSW LSTDRQWVKS
FKPADQADGG EALTRVELKK QNLF
//
