ID B8CF75_THAPS Unreviewed; 374 AA.
AC B8CF75; B8LBK0;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=HSF-type DNA-binding domain-containing protein {ECO:0000259|Pfam:PF00447};
GN ORFNames=THAPSDRAFT_11667 {ECO:0000313|EMBL:EED87752.1},
GN THAPSDRAFT_24396 {ECO:0000313|EMBL:EED87333.1};
OS Thalassiosira pseudonana (Marine diatom) (Cyclotella nana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=35128 {ECO:0000313|EMBL:EED87752.1, ECO:0000313|Proteomes:UP000001449};
RN [1] {ECO:0000313|EMBL:EED87752.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED87752.1};
RX PubMed=15459382; DOI=10.1126/science.1101156;
RA Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D.,
RA Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M., Brzezinski M.A.,
RA Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S., Detter J.C.,
RA Glavina T., Goodstein D., Hadi M.Z., Hellsten U., Hildebrand M.,
RA Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N., Lau W.W., Lane T.W.,
RA Larimer F.W., Lippmeier J.C., Lucas S., Medina M., Montsant A., Obornik M.,
RA Parker M.S., Palenik B., Pazour G.J., Richardson P.M., Rynearson T.A.,
RA Saito M.A., Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A.,
RA Wilkerson F.P., Rokhsar D.S.;
RT "The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and
RT metabolism.";
RL Science 306:79-86(2004).
RN [2] {ECO:0000313|EMBL:EED87752.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED87752.1};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
RN [3] {ECO:0000313|EMBL:EED87752.1}
RP GENOME REANNOTATION.
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED87752.1};
RG Diatom Consortium;
RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., Detter J.C.,
RA Schmutz J., Lindquist E., Shapiro H., Lucas S., Glavina del Rio T.,
RA Bruce D., Pitluck S., Rokhsar D., Armbrust V.;
RL Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS999415; EED87333.1; -; Genomic_DNA.
DR EMBL; CM000653; EED87752.1; -; Genomic_DNA.
DR RefSeq; XP_002294972.1; XM_002294936.1.
DR RefSeq; XP_002296637.1; XM_002296601.1.
DR PaxDb; 35128-Thaps11667; -.
DR EnsemblProtists; EED87333; EED87333; THAPSDRAFT_24396.
DR EnsemblProtists; EED87752; EED87752; THAPSDRAFT_11667.
DR GeneID; 7445421; -.
DR GeneID; 7449467; -.
DR KEGG; tps:THAPSDRAFT_11667; -.
DR KEGG; tps:THAPSDRAFT_24396; -.
DR eggNOG; ENOG502SSDF; Eukaryota.
DR HOGENOM; CLU_740798_0_0_1; -.
DR OMA; HCAARER; -.
DR Proteomes; UP000001449; Chromosome 11.
DR Proteomes; UP000001449; Chromosome 22.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001449}.
FT DOMAIN 18..92
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF00447"
FT REGION 118..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 40188 MW; ABF7AB8928F0852F CRC64;
MASASAPPPA KDEKTIPFLR SLTEMLQNNK ELISFVPGKK TATETIQGKI LVHDRIRVQT
EVLPIYFNHA SFASLRRQLS YFSFIRVGKG RQGGVTYVNE GVMVLSDILR LKRRTAQSGG
GGAAAAKGAA AGKEKSVEQQ QPSQSASLED VASAVLKGTL HAVKTNQYLD TDTAVAAAAA
STSATHHHGP SNITSSSVCR TNSTTNSSSA SSDNAESTGN NNNGNTDNKD IPRNISPSKL
PFKSSDSKRP LSQNKSGSVA ISRKDCPRLH RLLYVNNVVP FIHLPPKMKR SKSNEENEDG
SITDGNAKVV AAAPPSKKAR RGSKQEENTA GTPKSKQHQQ RRQHQEELFQ HCAARERTTS
ESAISALLAL GVQQ
//
