ID B8CWD9_HALOH Unreviewed; 503 AA.
AC B8CWD9;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=NAD-dependent epimerase/dehydratase {ECO:0000313|EMBL:ACL69608.1};
GN OrderedLocusNames=Hore_08520 {ECO:0000313|EMBL:ACL69608.1};
OS Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562).
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halothermotrichaceae;
OC Halothermothrix.
OX NCBI_TaxID=373903 {ECO:0000313|EMBL:ACL69608.1, ECO:0000313|Proteomes:UP000000719};
RN [1] {ECO:0000313|EMBL:ACL69608.1, ECO:0000313|Proteomes:UP000000719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H 168 / OCM 544 / DSM 9562 {ECO:0000313|Proteomes:UP000000719};
RX PubMed=19145256; DOI=10.1371/journal.pone.0004192;
RA Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H.,
RA Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.;
RT "Genome analysis of the anaerobic thermohalophilic bacterium
RT Halothermothrix orenii.";
RL PLoS ONE 4:E4192-E4192(2009).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
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DR EMBL; CP001098; ACL69608.1; -; Genomic_DNA.
DR AlphaFoldDB; B8CWD9; -.
DR STRING; 373903.Hore_08520; -.
DR KEGG; hor:Hore_08520; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_039511_1_0_9; -.
DR OrthoDB; 9772736at2; -.
DR Proteomes; UP000000719; Chromosome.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42687; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR42687:SF1; L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000719}.
FT DOMAIN 4..175
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 503 AA; 58161 MW; DC501BC849E08ADB CRC64;
MTKVFLTGST GTMGQATLKA LLKADSFEII VLVRDTKKDR KIIKPYIKEK NLQVYYGDLT
NYNDVLKCMV GADIVLHCAA LVSPAADYCP EAAMNINYGS TINIIKAIKA QPDWEEIRLV
YIGTVAKTGD RMPPIHWGRV GDPIKPSIHD YYAVSKVAAE RAVIESGLKY WVSLRQTGII
SEKMTEIKAP IIFHNCLDNV LEYITEKDSG VLMRNCCNDL PDDFWRHIYN IGGGPGCRMS
SYEMFKGLFE SLGINNLENV ISSKWFAIRN FHGQYYLDSD KLNDYLNFRS QNKQYFYKLY
LKKLRLFLPI ARTLTRVPGG EKLIGKIIKK QFKKLLLDER GTLNWIVNDK KEFIEPFFIS
IEKWDEIPLL YKFKHFTDWD KAIWIDHGYD ESKKESELSI EDLEGAAEFR GGRLLSNSME
KGDWQTKLEW KCAFGHKFTA SPRLILEGGH WCPVCERKSW NYHEIAKRSP FFAQVWYSLH
DRDEPLREYP KKVSELDVFP ASL
//
