ID B8EKG9_METSB Unreviewed; 435 AA.
AC B8EKG9;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Chloride channel core {ECO:0000313|EMBL:ACK51339.1};
GN OrderedLocusNames=Msil_2409 {ECO:0000313|EMBL:ACK51339.1};
OS Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB
OS 13906 / BL2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Beijerinckiaceae; Methylocella.
OX NCBI_TaxID=395965 {ECO:0000313|EMBL:ACK51339.1, ECO:0000313|Proteomes:UP000002257};
RN [1] {ECO:0000313|EMBL:ACK51339.1, ECO:0000313|Proteomes:UP000002257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2
RC {ECO:0000313|Proteomes:UP000002257};
RX PubMed=20472789; DOI=10.1128/JB.00506-10;
RA Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B.,
RA Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.;
RT "Complete genome sequence of the aerobic facultative methanotroph
RT Methylocella silvestris BL2.";
RL J. Bacteriol. 192:3840-3841(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001280; ACK51339.1; -; Genomic_DNA.
DR RefSeq; WP_012591408.1; NC_011666.1.
DR AlphaFoldDB; B8EKG9; -.
DR STRING; 395965.Msil_2409; -.
DR KEGG; msl:Msil_2409; -.
DR eggNOG; COG0038; Bacteria.
DR HOGENOM; CLU_015263_7_0_5; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000002257; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd01031; EriC; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR45711:SF6; CHLORIDE CHANNEL PROTEIN; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 4: Predicted;
KW Chloride {ECO:0000256|ARBA:ARBA00023214};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002257};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 435 AA; 44075 MW; AC33E0095FEB33C6 CRC64;
MQTASNRSSL TALALLSVLA GAGAGLVCGL FRLALDAAAQ LRAAFPQTWT GSSWSGCLIL
MGVAATATAT AALLVRRIAP TAIGSGIPHV EAVIAVETPP APFILLPVKF IGGVLAMGSG
LALGREGPCV QMGATLAQLL GQIFRRDWPD RQTLLAAGAG AGLAAAFNAP LAGAAFVLEE
LLRRFDLRAA FAGLGASMSA IVVARLFTGA APDFLLPQLP LPDARDFALC LGLGVVAGGF
GSLYNHLVLE ALDRSDAMVR VPIELQAAVA GAFIGALGWF APSLVGGGDG MTQALLTGAP
ALALIPLAFL LRLFLSAASY AAGTPGGLFA PMLVLGAQIG YFFGAALHPF MAAGESHAVL
FAVVGMAAFF TAVVRAPLTG MILVTEMTGS SAALLPMLGA CFTAMGFATL LGGKPLYDSL
KERSAHPHEA GPGKK
//
