ID B8EMQ2_METSB Unreviewed; 439 AA.
AC B8EMQ2;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Dihydroorotase, multifunctional complex type {ECO:0000313|EMBL:ACK52731.1};
DE EC=3.5.2.3 {ECO:0000313|EMBL:ACK52731.1};
GN OrderedLocusNames=Msil_3849 {ECO:0000313|EMBL:ACK52731.1};
OS Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB
OS 13906 / BL2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Beijerinckiaceae; Methylocella.
OX NCBI_TaxID=395965 {ECO:0000313|EMBL:ACK52731.1, ECO:0000313|Proteomes:UP000002257};
RN [1] {ECO:0000313|EMBL:ACK52731.1, ECO:0000313|Proteomes:UP000002257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2
RC {ECO:0000313|Proteomes:UP000002257};
RX PubMed=20472789; DOI=10.1128/JB.00506-10;
RA Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B.,
RA Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.;
RT "Complete genome sequence of the aerobic facultative methanotroph
RT Methylocella silvestris BL2.";
RL J. Bacteriol. 192:3840-3841(2010).
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DR EMBL; CP001280; ACK52731.1; -; Genomic_DNA.
DR RefSeq; WP_012592799.1; NC_011666.1.
DR AlphaFoldDB; B8EMQ2; -.
DR STRING; 395965.Msil_3849; -.
DR KEGG; msl:Msil_3849; -.
DR eggNOG; COG0044; Bacteria.
DR HOGENOM; CLU_015572_1_0_5; -.
DR OrthoDB; 9803027at2; -.
DR Proteomes; UP000002257; Chromosome.
DR GO; GO:0004151; F:dihydroorotase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd01317; DHOase_IIa; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR006680; Amidohydro-rel.
DR InterPro; IPR004722; DHOase.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR00857; pyrC_multi; 1.
DR PANTHER; PTHR43668; ALLANTOINASE; 1.
DR PANTHER; PTHR43668:SF2; ALLANTOINASE; 1.
DR Pfam; PF01979; Amidohydro_1; 1.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ACK52731.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002257}.
FT DOMAIN 67..435
FT /note="Amidohydrolase-related"
FT /evidence="ECO:0000259|Pfam:PF01979"
SQ SEQUENCE 439 AA; 46976 MW; 8A386EF0952DC6C1 CRC64;
MNIPVSPSVA HQPLALVNGR LVDGQTYDCV RGGILILDGK ILDLGPEVAP KNLPVHSRVI
DCGGDFIAPG LIDMRAFVGE PGGEHRETIA TATAAAAAGG VTTILARPDT NPPVDEPAVV
DFLLRRARDT GRVRLIPCAA MTQGLRGEEI AEIGLLQQAG ALAFSDGAHS IANSRVLRRV
LSYARDFDAL IIHYAEDRDL AAEGVMNEGE FATRLGLSGI PREAEAIALD RDIRLVNLTG
ARYHAALVTT TLSLDIIERA KAAGLPVTAG TSINHLTLNE SDIGDYRTFL KLAPPLRRED
ERRALVEALS SGLIDVIVSD HNPQDVETKR LPFAEAENGA IGLETMLAAG LRLVASGEVS
LQRLIGAMTL RPAEILGLPQ GRLRVGAPAD VIRFDAEAAY VVDPSKLRSR SKNTPFDEAT
MEGRVKLTLV EGRIVFEEE
//
