ID B8EMQ6_METSB Unreviewed; 482 AA.
AC B8EMQ6;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN OrderedLocusNames=Msil_3853 {ECO:0000313|EMBL:ACK52735.1};
OS Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB
OS 13906 / BL2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Beijerinckiaceae; Methylocella.
OX NCBI_TaxID=395965 {ECO:0000313|EMBL:ACK52735.1, ECO:0000313|Proteomes:UP000002257};
RN [1] {ECO:0000313|EMBL:ACK52735.1, ECO:0000313|Proteomes:UP000002257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2
RC {ECO:0000313|Proteomes:UP000002257};
RX PubMed=20472789; DOI=10.1128/JB.00506-10;
RA Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B.,
RA Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.;
RT "Complete genome sequence of the aerobic facultative methanotroph
RT Methylocella silvestris BL2.";
RL J. Bacteriol. 192:3840-3841(2010).
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DR EMBL; CP001280; ACK52735.1; -; Genomic_DNA.
DR AlphaFoldDB; B8EMQ6; -.
DR STRING; 395965.Msil_3853; -.
DR KEGG; msl:Msil_3853; -.
DR eggNOG; COG2199; Bacteria.
DR HOGENOM; CLU_565970_0_0_5; -.
DR OrthoDB; 9812260at2; -.
DR Proteomes; UP000002257; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002257};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 336..471
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 482 AA; 51033 MW; 3D10E5FFD17DA6F6 CRC64;
MPPYGGCFLA SLPLKQSSPR PDLRILSASA ELEKLGLWLV TAVAGCILLL WFVPSAAALA
PSGWSKMTAN AAAGMLAAAG SLALSGPRRS SLMLRLSAIA AWAVLALGCL TLLEYAYGPI
GIDHWLPRSS VGSNDGRPSP QTALGFALVG LCLALGSHPG RKLGTLSDLG AISLIALVLV
LVSGYVYQMV ELVGLSKANL SSPQTVFCFF LLSCVIAARR ASAGGWLSFW FDGGIGSRVA
RLVFPLVVLT PFVAFAAVGY LDSADIFPAA YTRAVETPII VLAALAMIAW MGRLTNKLER
ELRYQSLKDQ LTNVLNRRGF FTVADYAMKN AIRLKTGLTL FYFDLDGLKK VNDSLGHKAG
SELITRFADV LVATFRKTDV IGRIGGDEFV VLASDSSGTA EAMLARMAAI VAARAMSDPL
LEISYSSGYA ETSSPATVAI DDLIHQADKM MYERKQLKKA AGSTTGALAK TNRLLPSPSA
TG
//
