ID B8FFK0_DESAL Unreviewed; 832 AA.
AC B8FFK0;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=PAS/PAC sensor signal transduction histidine kinase {ECO:0000313|EMBL:ACL04260.1};
GN OrderedLocusNames=Dalk_2567 {ECO:0000313|EMBL:ACL04260.1};
OS Desulfatibacillum aliphaticivorans.
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfatibacillaceae; Desulfatibacillum.
OX NCBI_TaxID=218208 {ECO:0000313|EMBL:ACL04260.1, ECO:0000313|Proteomes:UP000000739};
RN [1] {ECO:0000313|EMBL:ACL04260.1, ECO:0000313|Proteomes:UP000000739}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK-01 {ECO:0000313|EMBL:ACL04260.1,
RC ECO:0000313|Proteomes:UP000000739};
RX PubMed=21651686; DOI=10.1111/j.1462-2920.2011.02516.x;
RA Callaghan A.V., Morris B.E., Pereira I.A., McInerney M.J., Austin R.N.,
RA Groves J.T., Kukor J.J., Suflita J.M., Young L.Y., Zylstra G.J., Wawrik B.;
RT "The genome sequence of Desulfatibacillum alkenivorans AK-01: a blueprint
RT for anaerobic alkane oxidation.";
RL Environ. Microbiol. 14:101-113(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001322; ACL04260.1; -; Genomic_DNA.
DR RefSeq; WP_015947333.1; NC_011768.1.
DR AlphaFoldDB; B8FFK0; -.
DR KEGG; dal:Dalk_2567; -.
DR eggNOG; COG3829; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_388691_0_0_7; -.
DR Proteomes; UP000000739; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ACL04260.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000739};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 348..419
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 422..474
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 493..563
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 564..617
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 740..827
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 465..492
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 832 AA; 93472 MW; 7A8390F223B4A9E5 CRC64;
MAKRSNKKES PEGALRQIVS VLALLAFLSI VTGGVLYVSF LQKAAVSEAD HQAVNRIKLV
ARHLSDSLTE NERPVKTLAG MRRIVRALET TDLEATEQAN RILDHFKETL NADVCYLIDV
TGLTIASSNR HFTDSFVGKN FGFRPYFQKA MEGRTATYLA LGSVSDKRGV YSSHPVMGSD
GELAGVVVIK ALVDLIESSL TSRPEEDVLV ADPNGVVFIS SKKQWLLKTL WPLNEKQINQ
VRDSQQFGPG PWSWIGFRPT DSPDTVELKG ARFLMHEEPI RFFPGWSAYY IQSEEAISQR
VSSNLFRVTG IVVITSIVLV GLLVFLLYTR ALVEINRRIM AEGALRQSEE RYRAIYHNTP
AMLHSINSKG RLVSVSDHWL KALQYETGQV IGKHLGDFMT PSSAEYLRET MMPEFLRTGE
CIDVPYQFVK KNGEVMDVLL SAIGERDEEG NFVRSLAVSV DVTEQKKAQE ALNQAQEKLS
QHSQELERQV FRRTEEISSI LKYTPNLVHI KDADGRYIMV NRRYEEIFGI SNEDVRGRTQ
HESMPREYAD AFREVDHRVL SEKKPVRSEY VVRVDGEDHS YLSVKFPIYD EQGRIHAIGG
ISTDVTEIKK AQEALRRLSN RMIISQEAER QAIARELHDE LGQILTVLRM DAVWFKKRLK
DSDAATQERA SAMCELIDKT IEDVRGIAVR LRPGVLDDLG LVDALEWYTS DFERRTGITC
IFEHDNIPNL GNAISTAAYR IAQEALTNVV RHASTDRADV SLSFDQEEFT LIISDNGVGY
DGGMVEESEG LGIAGMRERA MLAGGTLEVE AGEDAGSRII FRIKVSGANK EK
//
