ID   B8FJX4_DESAL            Unreviewed;       265 AA.
AC   B8FJX4;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   RecName: Full=Pyruvate dehydrogenase complex repressor {ECO:0000256|ARBA:ARBA00039592};
GN   OrderedLocusNames=Dalk_0697 {ECO:0000313|EMBL:ACL02402.1};
OS   Desulfatibacillum aliphaticivorans.
OC   Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC   Desulfatibacillaceae; Desulfatibacillum.
OX   NCBI_TaxID=218208 {ECO:0000313|EMBL:ACL02402.1, ECO:0000313|Proteomes:UP000000739};
RN   [1] {ECO:0000313|EMBL:ACL02402.1, ECO:0000313|Proteomes:UP000000739}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AK-01 {ECO:0000313|EMBL:ACL02402.1,
RC   ECO:0000313|Proteomes:UP000000739};
RX   PubMed=21651686; DOI=10.1111/j.1462-2920.2011.02516.x;
RA   Callaghan A.V., Morris B.E., Pereira I.A., McInerney M.J., Austin R.N.,
RA   Groves J.T., Kukor J.J., Suflita J.M., Young L.Y., Zylstra G.J., Wawrik B.;
RT   "The genome sequence of Desulfatibacillum alkenivorans AK-01: a blueprint
RT   for anaerobic alkane oxidation.";
RL   Environ. Microbiol. 14:101-113(2012).
CC   -!- FUNCTION: Transcriptional repressor for the pyruvate dehydrogenase
CC       complex genes aceEF and lpd. {ECO:0000256|ARBA:ARBA00037357}.
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DR   EMBL; CP001322; ACL02402.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8FJX4; -.
DR   KEGG; dal:Dalk_0697; -.
DR   eggNOG; COG2186; Bacteria.
DR   HOGENOM; CLU_017584_9_0_7; -.
DR   Proteomes; UP000000739; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43537:SF34; PYRUVATE DEHYDROGENASE COMPLEX REPRESSOR; 1.
DR   PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00895; FCD; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000739};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          13..83
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
FT   REGION          242..265
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   265 AA;  29715 MW;  14DE30B30DF9B031 CRC64;
     MKDNPMFSPV RVGRAGEDVA LQIEAAIMDG RVKPGERLPS ERDLHVQFGA SRGVVREALR
     ALKQKGLIEI KKGAKGGAFI KEAELHNASE SLGLFLKLQR ISAQSLIEFR ESMDRTITTL
     AITRADAEEK QQLLEGAMQL GNLLNKEDPD MDAVHELDRR LNIRLARMTK NPVFEWIMRA
     VQLGLSSHDA VLYEDDEYRS RTAGNWRETA QAIADNEPLK ALSYIGYHYV MLQKCLEDRE
     VQENNQGADG QDADFWASTP DIPGP
//