ID B8FKF8_DESAL Unreviewed; 676 AA.
AC B8FKF8;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=UvrD/REP helicase {ECO:0000313|EMBL:ACL01773.1};
GN OrderedLocusNames=Dalk_0063 {ECO:0000313|EMBL:ACL01773.1};
OS Desulfatibacillum aliphaticivorans.
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfatibacillaceae; Desulfatibacillum.
OX NCBI_TaxID=218208 {ECO:0000313|EMBL:ACL01773.1, ECO:0000313|Proteomes:UP000000739};
RN [1] {ECO:0000313|EMBL:ACL01773.1, ECO:0000313|Proteomes:UP000000739}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK-01 {ECO:0000313|EMBL:ACL01773.1,
RC ECO:0000313|Proteomes:UP000000739};
RX PubMed=21651686; DOI=10.1111/j.1462-2920.2011.02516.x;
RA Callaghan A.V., Morris B.E., Pereira I.A., McInerney M.J., Austin R.N.,
RA Groves J.T., Kukor J.J., Suflita J.M., Young L.Y., Zylstra G.J., Wawrik B.;
RT "The genome sequence of Desulfatibacillum alkenivorans AK-01: a blueprint
RT for anaerobic alkane oxidation.";
RL Environ. Microbiol. 14:101-113(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
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DR EMBL; CP001322; ACL01773.1; -; Genomic_DNA.
DR AlphaFoldDB; B8FKF8; -.
DR KEGG; dal:Dalk_0063; -.
DR eggNOG; COG0210; Bacteria.
DR HOGENOM; CLU_004585_8_1_7; -.
DR Proteomes; UP000000739; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000000739}.
FT DOMAIN 33..329
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 54..61
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 676 AA; 76924 MW; DDE2892C48B9C102 CRC64;
MENNAPFVPP EITDADIEWA TELLGLPKNA FLGEDGDDPR KEVLKDMTTF DVSACPGSGK
TTLLVAKLAI LANKWSHRTS GICVLSHTNA ARDEIEKRLG SSAVGRQLLN YPHYIGTIHG
FVDQFLALPW LRSKNCPIKI IDTDICQNFR WKYVFFRTSK WSSQMQKILK EKSLRGDKIL
IQSSDFTLTN VKYGEKTKLY KVMKDSCVLS TEKGYFCFEE MFMWAKELMD TTPSIILTIR
KRFPLSFIDE VQDNSDSQTA ILQRIFTENG NSAIQQRFGD ENQAIYSSPE SQSAPGNILP
IDEKNKKVLP NSHRFCQHIA DLSGPLSMTA DTCSLEGHGP KCRHISCYSE DGNHTIFLFD
DNSINRVLDA FGHLLIATFS DESLRHGVFT AVGHIHKPKR DEPKPCHVQH YWPDYNPELC
KKEPRPSSLL QYIHVGLGKS QRAGISHPAA EKIAEGLFRL AGMSENPTRV SRRGFCHRSV
LKALENRPKA KGVYLDLLHS LVVDRNLPTR DEWKAQSPIY YKLASIIAEA PINKPEANSF
LQWHEFAAIP QPDEEPTTCM DNIYRYSHDG REVPIRVGSI HSVKGETHTA TLVLETYWHK
HNLESIFDWI CDNNAGCCKK EKRNNPRLKT HYVAMTRPTH LLCLAMKKSC FEDQEGNLNQ
EKIDKLTERG WKYQVV
//
