ID   B8FKI7_DESAL            Unreviewed;      1414 AA.
AC   B8FKI7;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:ACL01802.1};
GN   OrderedLocusNames=Dalk_0092 {ECO:0000313|EMBL:ACL01802.1};
OS   Desulfatibacillum aliphaticivorans.
OC   Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC   Desulfatibacillaceae; Desulfatibacillum.
OX   NCBI_TaxID=218208 {ECO:0000313|EMBL:ACL01802.1, ECO:0000313|Proteomes:UP000000739};
RN   [1] {ECO:0000313|EMBL:ACL01802.1, ECO:0000313|Proteomes:UP000000739}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AK-01 {ECO:0000313|EMBL:ACL01802.1,
RC   ECO:0000313|Proteomes:UP000000739};
RX   PubMed=21651686; DOI=10.1111/j.1462-2920.2011.02516.x;
RA   Callaghan A.V., Morris B.E., Pereira I.A., McInerney M.J., Austin R.N.,
RA   Groves J.T., Kukor J.J., Suflita J.M., Young L.Y., Zylstra G.J., Wawrik B.;
RT   "The genome sequence of Desulfatibacillum alkenivorans AK-01: a blueprint
RT   for anaerobic alkane oxidation.";
RL   Environ. Microbiol. 14:101-113(2012).
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DR   EMBL; CP001322; ACL01802.1; -; Genomic_DNA.
DR   RefSeq; WP_012609242.1; NC_011768.1.
DR   KEGG; dal:Dalk_0092; -.
DR   eggNOG; COG1413; Bacteria.
DR   eggNOG; COG2199; Bacteria.
DR   eggNOG; COG3899; Bacteria.
DR   HOGENOM; CLU_253456_0_0_7; -.
DR   Proteomes; UP000000739; Chromosome.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR004155; PBS_lyase_HEAT.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00567; EZ_HEAT; 3.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000739}.
FT   DOMAIN          52..187
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   REGION          983..1019
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        987..1019
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1414 AA;  156231 MW;  78737322065581E9 CRC64;
     MEELADLVFF LENSGKDPTS MIFDDELTGL RNRRFIKNHL EFRVQWGDLK ARPTSMVFVD
     IDNLDQINDA LGRDLGTAVL KHLAELVKQA APEGSTPVRY GADEFVILLP EEPKKTAVTI
     GRKLISAVHG APYISEDATL EIPFTISVSI TTAPEDAESD KTFVERALTA LKMAKDLGGD
     RAINAAEISP ENEAAESMLH KDAAKNAGRK SQLAQVSQAL KRFGKRESQL VLVEGGPGMG
     KTSFLDTINT QLSKTKVARI RLAGVTQELF RPYYLVSNLV QELLYRRKDK GGEILANLDP
     VALCALSSAF VPSGDMRIHT RQAPDVDLGD VAQKREHVFN AMASIIPKLI ENKPLIVLVD
     DLHMVDEASL LIFKHLIAQK SLPLFLCGSG PDSLQADGEH GPLWRFVQSV IEMAPLETIH
     LTPLSPQEIE AHFNKLYPGV RLPEQLCEDI AQVSQGNPLF FNGIMFKLVF DEKIRRADGH
     WVVDPIEEDY LPRSMDEIIS QKVASLDQES QALLDRASAF GDRVTLSLLT GSSEMDEAAV
     LDFLDNAAAQ GLVSATFHMN DENIRFLGNQ VRQVIYGKIG QEEKERLHEN IGDYQEELYK
     KRLMPSPAIL AYHYQRSANL EKAKLYEQIQ AQQNEMIFNP DEAESYSGRT PEWDDDAQAP
     DQPLAPEHYP LAAKVIRALL IAIRNTKLYP TGSDLTANAV NKFKEVLETV LVHTPRLTIV
     LEKDVIYANG DALDIPEIKT VSEAFSGFMG TMDLKSIAFS HGATLAELVR LVEGISEVDP
     KNIHKRFWKE FSTENRLRRV QVKQVTYTQV SGEEQQTSGA SAKEAELGSE EQVLAAKVVK
     TLLSSASKLK LYPASGPVAQ ESIEEVMKIL KVFLDKHEVM TLAGVDQSLL LNGNKVDARV
     FDKLTPFMLK FLESACLKSV TFYQKASKQE LTVFLANVGK QPQDGTADEF WANVGMENKL
     STIYFNISVY DVLADQIALQ AAGEGQGGQE EEEEVEEPLE LESDEGDLEM PPESEEQDIS
     LEPSVENIRD LFLKGNEKGV ARVLEVLFYK YSEKEEGRRE QVLETCRELL NAPELSPEPR
     FAPLLVDPLL AVLPAESDAQ LLENMASLLY DTAANFVRIG EYSLATWIFG HFARRREAME
     MEDPEGIIPE ALTRQPEGDM ALTLMADVAS GEGFRQQSAF ALIGGMGDSG VRLLLNIIKD
     NDDVRTRQIA ASQLEKIGYQ AVEKLKQELV NENSGKRKAR IVEVIDTATT DLKTELTFLL
     ADSNTSVRKA GFALAERLNA PYVVNILSNL LDDERPEIAK EAVVCLGKTA APGSAGIIVK
     QMDVNKAPEL LEACCQALGR LADPEAIVPL SKILSYKKTL FSKKEYAASV RAAAAFALAG
     IPHKLAKGAL AAYADDPEPR VREAAQKVMG VSQD
//