ID B8GIL9_METPE Unreviewed; 769 AA.
AC B8GIL9;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=PAS/PAC sensor hybrid histidine kinase {ECO:0000313|EMBL:ACL16832.1};
GN OrderedLocusNames=Mpal_1518 {ECO:0000313|EMBL:ACL16832.1};
OS Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanoregulaceae; Methanosphaerula.
OX NCBI_TaxID=521011 {ECO:0000313|EMBL:ACL16832.1, ECO:0000313|Proteomes:UP000002457};
RN [1] {ECO:0000313|EMBL:ACL16832.1, ECO:0000313|Proteomes:UP000002457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1556 / DSM 19958 / E1-9c
RC {ECO:0000313|Proteomes:UP000002457};
RX PubMed=26543115; DOI=10.1128/genomea.01280-15;
RA Cadillo-Quiroz H., Browne P., Kyrpides N., Woyke T., Goodwin L., Detter C.,
RA Yavitt J.B., Zinder S.H.;
RT "Complete Genome Sequence of Methanosphaerula palustris E1-9CT, a
RT Hydrogenotrophic Methanogen Isolated from a Minerotrophic Fen Peatland.";
RL Genome Announc. 3:e01280-15(2015).
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DR EMBL; CP001338; ACL16832.1; -; Genomic_DNA.
DR RefSeq; WP_012618151.1; NC_011832.1.
DR AlphaFoldDB; B8GIL9; -.
DR STRING; 521011.Mpal_1518; -.
DR GeneID; 7271063; -.
DR KEGG; mpl:Mpal_1518; -.
DR eggNOG; arCOG02329; Archaea.
DR eggNOG; arCOG02386; Archaea.
DR eggNOG; arCOG02391; Archaea.
DR HOGENOM; CLU_000445_114_51_2; -.
DR OrthoDB; 115915at2157; -.
DR Proteomes; UP000002457; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACL16832.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000002457};
KW Transferase {ECO:0000313|EMBL:ACL16832.1}.
FT DOMAIN 7..124
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 214..266
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 267..340
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 344..397
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 410..626
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 645..765
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 59
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 699
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 769 AA; 85741 MW; 9BDEEEA4C0172EA0 CRC64;
MDPDPIRVLL VEDNPGDARL IREMLVEIHT DRYEVVHVER LEYALLHLNN EKFDTILLDL
NLPDAYGLST LVKIRAKAPH VPVIVVSGLG DEEMAIHALR EGAYTYLVKG QMSGHLLDRS
IRYSIERERM EQIVQLQRAR EYAENIVDTI RESLIVLDNR LRIVSANRSF YLDFHVTPEQ
VEGRFIHDLA DQEWNIPQFL ALLEKILHHS FQYEGLELDH EFPALGRRVM LLNARWVYEE
RGDTDRILLA MEDITERKRA EEALADEKER LAVTLWNIGE GVIVTDVGGS VGMMNRVAES
LTGWTASEAV GLPIDQVYQV INEKTRNHCV NPVAAVLKKE ETTDSSHFRL LIGKDGIERP
LGDSVAAVRD KDGKIIGVVI VFRDITAARR MEEDLAKNER LESIGVLAGG IAHDFNNALT
AIEGNIVVAK AHLKPEEKAY ERLSEAEMAA HRARDLTRQL LTFSRGGKPI KRQLRLNDLL
IDAVSFALSG SAVRKKFSIA EDLWPVEADE GQIRQVINNL VINADQAMPD GGILDVIGDN
VSLASDQVLS LKAGNYVRIA VKDHGIGIPK EFLSKIYEPY FTTKQKGSGL GLTVAYSILR
NHGGSLIVDS VTGGGSTFTL YIPASQMQLP VESVPSVHPL QGNERILWMD DETMIREVGG
EMLSLLGYRF AFAEEGDQAI ELYKAALESE SPFDAVILDL TGAGGLGGKE TIKQLLELDP
QVRAIVCSGY SNDPVMANHR EYGFRGVLTK PFTMKELDDQ IHLVIGTEE
//
