ID B8HGS5_PSECP Unreviewed; 978 AA.
AC B8HGS5;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
DE Flags: Precursor;
GN OrderedLocusNames=Achl_3384 {ECO:0000313|EMBL:ACL41341.1};
OS Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP
OS 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6) (Arthrobacter
OS chlorophenolicus).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Pseudarthrobacter.
OX NCBI_TaxID=452863 {ECO:0000313|EMBL:ACL41341.1, ECO:0000313|Proteomes:UP000002505};
RN [1] {ECO:0000313|EMBL:ACL41341.1, ECO:0000313|Proteomes:UP000002505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 /
RC NCIMB 13794 / A6 {ECO:0000313|Proteomes:UP000002505};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.;
RT "Complete sequence of chromosome of Arthrobacter chlorophenolicus A6.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001341; ACL41341.1; -; Genomic_DNA.
DR AlphaFoldDB; B8HGS5; -.
DR STRING; 452863.Achl_3384; -.
DR CAZy; GH33; Glycoside Hydrolase Family 33.
DR KEGG; ach:Achl_3384; -.
DR eggNOG; COG1470; Bacteria.
DR eggNOG; COG4409; Bacteria.
DR HOGENOM; CLU_299110_0_0_11; -.
DR Proteomes; UP000002505; Chromosome.
DR GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR018905; A-galactase_NEW3.
DR InterPro; IPR047589; DUF11_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR NCBIfam; TIGR01451; B_ant_repeat; 1.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR Pfam; PF10633; NPCBM_assoc; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000313|EMBL:ACL41341.1};
KW Hydrolase {ECO:0000313|EMBL:ACL41341.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..978
FT /note="exo-alpha-sialidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002870791"
FT DOMAIN 68..387
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
FT DOMAIN 423..492
FT /note="Alpha-galactosidase NEW3"
FT /evidence="ECO:0000259|Pfam:PF10633"
SQ SEQUENCE 978 AA; 101708 MW; CAB770183E0FAA25 CRC64;
MGQAAGIGAL AVALLAGTGL PAQAAPIPST SPTAPPGAFQ ETNLAADRTA NNFFYRIPAL
SYLGNGVVLA AWDGRPGSAA DAPNPNSIVQ RRSTDGGRTW GPVQVIAAGH VGDAAAPKYG
YSDPSYVYDA EAGKVFAFFV YSKDQGFGGS QFGNDDADRN VISSAVIESS DGGTTWSQPR
LITGVTKPGT SKTNPVAGDV RSNFASSGEG IQLKYGPYKG RLIQQYAGDI RQADGSNRIQ
AYSVYSDDHG ATWHKGANVG DRMDENKTVE LSDGRVLLNS RDNANQGYRK VAVSTDGGAT
YGPVTQDTEL PDPANNGAIA RMFPNAAQGT ADAKKLIFTN ANSKTGRENV SARVSCDDGA
TWPGVRTIRS GFSAYSTVTR LDEGRLGVLY EANYTDNMPF AAFDDAWLNY ACAPLSVPAV
TTAPGATKQV PVTVTNQEAA TLSGATVTVY TPSGWSATTV PVPDVAPGAS ATVNVDLTAP
ANASGPQNLN AAFTTADGRV SQAAFTATVP VAPQVGLTIT GAAPDRDVAA SPYKAGDVVS
YTFNVKSTAN VTANSVPLSG TFEAGFLPPA PGAPSSPNCR YNNLAAGASY TCTTARHTVT
AEDMARGYFV PQATFSITAS ATPSLTRTVA FTGAAVALRD GLVSATITGS RNDAGRDLAA
QPYTAGEAFP YKFDVTNTSP LVEKVVPTAG NFSPFVPDGP GNCRYNVLPA GQSYTCATPR
HTVTAEEAAQ GFFIPETNWD VSAAGQTIRT YGVNGGEVDL KVRDASLDGT IAAEWTDKDG
DRYASAGDTV TYTYTVGNAG NVPLTGVAAP AAGISEPSLA AGSSVTATRD YVLTAADITA
GKLDAVSFSA TGDNGTRRAT ASVSGGGIQL ELQPAQPESE PALTVQDFDG QTPPFDLKTQ
DKYRNGQKVV LEGLDYGQWY YVYLNKRSQR IGWLFPTTAN TVEFILPAGI QNGRDDVVVL
DKDGKQVSFD RLQVTPKG
//
