ID B8HRH4_CYAP4 Unreviewed; 1330 AA.
AC B8HRH4;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Cyan7425_1795 {ECO:0000313|EMBL:ACL44162.1};
OS Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Cyanothecaceae;
OC Cyanothece.
OX NCBI_TaxID=395961 {ECO:0000313|EMBL:ACL44162.1};
RN [1] {ECO:0000313|EMBL:ACL44162.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PCC 7425 {ECO:0000313|EMBL:ACL44162.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T.,
RA Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L.,
RA Sato H., Zhao L., Sherman L., Pakrasi H., Richardson P.;
RT "Complete sequence of chromosome Cyanothece sp. PCC 7425.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001344; ACL44162.1; -; Genomic_DNA.
DR STRING; 395961.Cyan7425_1795; -.
DR KEGG; cyn:Cyan7425_1795; -.
DR eggNOG; COG0784; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_252135_0_0_3; -.
DR OrthoDB; 5555607at2; -.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 6.
DR CDD; cd17580; REC_2_DhkD-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 7.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 7.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 3.
DR Pfam; PF08448; PAS_4; 3.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 5.
DR SMART; SM00091; PAS; 7.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 7.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 4.
DR PROSITE; PS50112; PAS; 6.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ACL44162.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:ACL44162.1}.
FT DOMAIN 30..85
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 137..209
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 213..265
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 291..361
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 364..416
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 417..491
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 486..545
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 553..622
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 814..885
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 890..943
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 968..1186
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1207..1325
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 790..817
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 934..964
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1256
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1330 AA; 150215 MW; 574BA30CA593E2EA CRC64;
MTAEGPFTSP VHQSSLAEEA FFFDLSLDLL AVVGLDGYFK RINPMFSQTL GYSATELLTS
PFLDFVHPDD RAATLAEMEQ LKGGTPTLAF ENRYLTREGD YRWLSWTASP QLDRAVIYCV
ARDVTQQKQT EIALRVSEER WQLALRGSND GIWDWNVQTN EVFFSARWKT MLGYEEDEIS
HHLEEWAKRV HPDDLAWVMQ AIQDHFAQKT PFYVAEHRVQ CKDGGYKWIL DRGQAIWDQD
GKVLRMVGSH TDVTERKTLE AALRTANETL EQRVAQRTAE LEQINRSLQA SELKFRTAIE
HIPDVFVIYD AHRRIQFVNR AGLALSGGSL PDFLGRRDEE IFPVEVTQTY LPLLQQAVAT
KRYQTGECTI ALPNREPYTI VVQYVPLLDG NGEIQQIFGI SHDITRRKQA EDATRRSEQQ
IRRILDSLFS FVGVMTPDGI LIEANRTALE AAALRPADVL GKPFEDTYWW SYSPELQTQL
RQAITRAAQG EMVRYDAIVR VREDQLITID FTLGPIFDEA GRVKYLIPSG IDITERKQAE
IALQQSQSQV QRQLAEIETI YQSAPIGLNI LDTDLRFVRI NQRLADMNGF SVEEHLGKTI
RDLLPDLADT AEALLRPILA TGEPLLNVEI RGETPAQPGV QQIWLESFLP LKQDDRIIGI
STVCEEITER KQAEEALRRS EERYRTLFET MEDGFCVIEI LFDANQTPID YRFLEINPAF
EQQTGLHQAV GKTARQLIPN LEDFWFETYG RVALTGEPLR FENGSAVMNR WFEVYAFPVG
QPEHHKVALL FKEISERKRL EAERQQAEIA LRENEDRLRM AIASAQLGTW DWNIVTGKLK
WDTGCKAMFG LGPDAEINME TFFAGVHPQD REQLKAMVQS RLNPASGGSF DTEYRTIGLQ
DKVERWLRSK GQAYYDANGN PLRFSGTVLD ITQQKQAEAH REQLLQQEQA AREAAERANR
IKDEFLAVLS HELRTPLNPI LGWSKLLQSP QISAQKLQQG LATIERNAKQ QVQLIDDLLD
TSRIIRGQLS LNLAVINLSE PILAALETVR LSAETKEIKL EVKLGSWLGQ IRGDVGRLQQ
VVWNLLSNAI KFTPPGGRIT VRLSQVDRWA QIQVRDTGKG IQPQFLPHVF ELFRQEDSST
TRSFGGLGLG LAIARQVVEA HGGTIMAASQ GEGQGATFTV LLPLIPAAIT NVPADPQPQP
LNIEQLRVMV VDDEADSLEV VKVVLEQQGA IVQALPSAPK ALQLLTEVPF DLLVSDIGMP
EMDGYTFIRQ VRTLPSSLNR NIPAIALTAY ASDMDQHQAL STGYQFHLAK PLEPEALVRA
ITRLGLPRPD
//
