ID   B8HVU7_CYAP4            Unreviewed;       525 AA.
AC   B8HVU7;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:ACL43125.1};
GN   OrderedLocusNames=Cyan7425_0738 {ECO:0000313|EMBL:ACL43125.1};
OS   Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Cyanothecaceae;
OC   Cyanothece.
OX   NCBI_TaxID=395961 {ECO:0000313|EMBL:ACL43125.1};
RN   [1] {ECO:0000313|EMBL:ACL43125.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC 7425 {ECO:0000313|EMBL:ACL43125.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L.,
RA   Sato H., Zhao L., Sherman L., Pakrasi H., Richardson P.;
RT   "Complete sequence of chromosome Cyanothece sp. PCC 7425.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; CP001344; ACL43125.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8HVU7; -.
DR   KEGG; cyn:Cyan7425_0738; -.
DR   eggNOG; COG1032; Bacteria.
DR   HOGENOM; CLU_021572_5_0_3; -.
DR   OrthoDB; 9801424at2; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd01335; Radical_SAM; 1.
DR   Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR   Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR   InterPro; IPR006158; Cobalamin-bd.
DR   InterPro; IPR025274; DUF4070.
DR   InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR   InterPro; IPR034530; HpnP-like.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR   PANTHER; PTHR43409:SF3; HYPOTHETICAL METHYLTRANSFERASE; 1.
DR   Pfam; PF02310; B12-binding; 1.
DR   Pfam; PF13282; DUF4070; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDF00303; hopanoid_C2-methyltransferase; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SMART; SM00729; Elp3; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
FT   DOMAIN          163..388
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|PROSITE:PS51918"
SQ   SEQUENCE   525 AA;  60500 MW;  7F03FC1A2F07B443 CRC64;
     MKALLFWPIL PNSFWSYRET LQLAGLHSTN PPLGLITIAA MLPSDWELRL FDRNVGLETE
     ADWQWCDLVI ISAMVIQRED FQDLIRRAIE LGKKVAVGGP YPTSYPEAAL EVGAHYLILD
     EGECTIPLFL EALHQGADRG IYRSPEKPDV TQTSIPRFDL LDLQAYMAVT VQFSRGCPFQ
     CEFCDIINLY GRKPRTKTPE QMLAELEVLY QIGWQRYVFI VDDNFIGNKR NAKAFLRALI
     PWMEERNYPF ILLTEASLNL AEDEELIELM VRAGFTIVFM GIETPDVDSL VGIHKLQNTR
     SSLIESCQKI TRKGLHIMSG FIIGFDNEKA GAGGRIQSFI EEAGIVQCQF SLLQALQNTA
     MWDRLKREGR LADGLGTFHQ GAIMNFVPTR PIAEITEEYI AAFWQIYDPT AYLKRAFRNF
     MMMNGWRGKT KRKLTTTELR LFLAICWRQG LLRSTRWRFW WQLGMIALRK PRLLFDYLVA
     LGAGEHFFHY RYEVREQLRQ QLAALQEREQ LESRITADAA EVVSI
//