ID   B8I9S8_METNO            Unreviewed;      1161 AA.
AC   B8I9S8;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Pyruvate ferredoxin/flavodoxin oxidoreductase {ECO:0000313|EMBL:ACL55331.1};
GN   OrderedLocusNames=Mnod_0287 {ECO:0000313|EMBL:ACL55331.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55331.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55331.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS 2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001349; ACL55331.1; -; Genomic_DNA.
DR   RefSeq; WP_015927043.1; NC_011894.1.
DR   AlphaFoldDB; B8I9S8; -.
DR   STRING; 460265.Mnod_0287; -.
DR   KEGG; mno:Mnod_0287; -.
DR   eggNOG; COG1014; Bacteria.
DR   eggNOG; COG4231; Bacteria.
DR   HOGENOM; CLU_009166_1_0_5; -.
DR   OrthoDB; 9803617at2; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR   CDD; cd02008; TPP_IOR_alpha; 1.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR046667; DUF6537.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR   PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR   Pfam; PF20169; DUF6537; 1.
DR   Pfam; PF01558; POR; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Pyruvate {ECO:0000313|EMBL:ACL55331.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207}.
FT   DOMAIN          731..918
FT                   /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01558"
FT   DOMAIN          942..1141
FT                   /note="DUF6537"
FT                   /evidence="ECO:0000259|Pfam:PF20169"
SQ   SEQUENCE   1161 AA;  126617 MW;  BFAC5ACDE52FF890 CRC64;
     MGRQSAVSSL RPVSLEDKYD LSREQVFITG TQAVIRMLLM QQARDRAAGL NTAGFVSGYR
     GSPIAGLDLN LYKARKVLEA ANIVFQPGLN EELAATAIWG AQQAEIRGEG RYDGVFGLWY
     GKGPGVDRAG DVFRHANTAG SSRYGGVLAL MGDDHTAESS TLAHQSEFHF VDVMMPILNP
     AGVQEILDYG LYGYAMSRYC GTWVAFKCVK DNIESTASVD ARLDRVRIVQ PDDFAMPPGG
     LNIRTPDVIL EQEARLQDYK RDAMMAFVRA NNLNRIILSG GRQPKIGVIT VGKSYLDVRQ
     ALDDLGLDEV KANDMGLRLY KVACPWPLSQ RELLAFAEGL DLIMVVEEKR SLIEVQVREE
     LYGTANQPIC VGKRDEAGRW LFPVKGALDP NDIAVALGER LLRYHRNDDL AGRVAALRQA
     QEILAATTDI AVRTPHFCAG CPHNSSTRIP EGARAYAGIG CHYMAQWMER GTDGCTQMGG
     EGANWIGEAP FSKRTHVFQN LGDGTYNHSG SLALRWAVDT GTTITYKILF NDAVAMTGGQ
     PHEGGLTVDR IAQQVRAEGV ERIALVTDEP HKYPSGMRWP EGLTIHHRDD LDTVQRDLAT
     VPGVSVLIYD QTCAAEKRRR RKRGRFPDPD KRVIINDLVC EGCGDCSVQS NCVAVQPLET
     EFGRKRRIDQ SSCNKDFSCL NGFCPSFVTV HGGKPRTHPL VPLPGTPDEG LPEPVLPPIE
     GTYNIIVTGV GGTGVVTVGA ILGMAAHLEG KGLGMIDMAG LAQKGGAVFS HVRLAQAQDD
     IHAIRVTAGA ADLILGCDLV VTGTRKVLAA VRPGRTHVVV NTAEIMPGDF TRRPDFSLPV
     ERIKRVIREK AGPAHADLTD ATGLAVAALG NAIAANMFML GYAWQRGRVP LSRAAILKAI
     ELNREAVPMN LAAFAWGRRA AAAPETLGAL KAATASDLSA DLDTLIARRV AFLTDYQDAA
     YAQRYARIVA SVREREAAVH PGGSPLTEAV ARSLFKLMAY KDEYEVARLY TDGHFEAQIR
     NTFEGEGLRY EFHLAPPLLA RTDPRTGRPR KMSFGPWVLR VFRMLARMKR LRGTALDPFG
     YTQERREERR LIGEFETLVA EILRDLTPAN HAVAVGLANL PLTIRGFGPV KAKSLAAAKQ
     EEAVLLTRFR APEAPLAAAA E
//