ID B8IUW1_METNO Unreviewed; 556 AA.
AC B8IUW1;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Beta-lactamase domain protein {ECO:0000313|EMBL:ACL59019.1};
GN OrderedLocusNames=Mnod_4141 {ECO:0000313|EMBL:ACL59019.1};
OS Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylobacterium.
OX NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL59019.1, ECO:0000313|Proteomes:UP000008207};
RN [1] {ECO:0000313|EMBL:ACL59019.1, ECO:0000313|Proteomes:UP000008207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC {ECO:0000313|Proteomes:UP000008207};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J.,
RA Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium nodulans ORS 2060.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001349; ACL59019.1; -; Genomic_DNA.
DR RefSeq; WP_015930668.1; NC_011894.1.
DR AlphaFoldDB; B8IUW1; -.
DR STRING; 460265.Mnod_4141; -.
DR KEGG; mno:Mnod_4141; -.
DR eggNOG; COG0595; Bacteria.
DR HOGENOM; CLU_008727_3_3_5; -.
DR OrthoDB; 9770211at2; -.
DR Proteomes; UP000008207; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd07714; RNaseJ_MBL-fold; 1.
DR Gene3D; 3.10.20.580; -; 1.
DR Gene3D; 3.40.50.10710; Metallo-hydrolase/oxidoreductase; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR InterPro; IPR042173; RNase_J_2.
DR InterPro; IPR041636; RNase_J_C.
DR PANTHER; PTHR43694; RIBONUCLEASE J; 1.
DR PANTHER; PTHR43694:SF1; RIBONUCLEASE J; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR Pfam; PF17770; RNase_J_C; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000008207};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 19..219
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 556 AA; 60601 MW; 6CF14E5B98C25AD3 CRC64;
MAKGDELVFV PLGGVGEIGM NAALYGFGPP TARKWIMVDC GMGFASEEHM PGVDLMYPDL
SFIEQQRENL LGILITHGHE DHIGALVELW PRLKVPVYAT GFTKSLIETR RLGEPGAPKI
DLREVRPNER MSFGPFEVEY VPVAHSIPEA NALAIRTAHG LVVHTGDWKL DDAPVVGNVT
SEEVFTRLGE EGVLALVCDS TNVTREGRSP SEAEVAAHLA ELIRSAPHRV AVTTFASNVA
RIRAVADAAQ ACGREVVAVG RAMDRVIDVA RECGYLDGLP EFREPEAYGY LPREKVVALL
TGSQGEPRAA LSRVSRDEHP EIALSPGDRV IFSSRAIPGN ERAIGAIIND LVEAGVEVVT
DRTELVHVSG HPRRDELAAM YRWTKPRIAV PVHGEPLHLA EHATFARKQG VEDVVKARNG
TLIRLAPGAP QIIDHVSHGR LYKDGMVLIT ETDRALPERR KLSFTGIISV AIAIDQHGEM
KGEPAIDLMG LPTYGRNGEA IIDIVEDVVE RTFGGLSRQK RRDSEAVENA VDRAIRAAVN
EVWGKKPACH VQVVEI
//
