ID B8LYL0_TALSN Unreviewed; 747 AA.
AC B8LYL0;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 03-MAY-2023, entry version 60.
DE SubName: Full=WD repeat protein {ECO:0000313|EMBL:EED23368.1};
GN ORFNames=TSTA_067960 {ECO:0000313|EMBL:EED23368.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED23368.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family.
CC {ECO:0000256|ARBA:ARBA00005264}.
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DR EMBL; EQ962652; EED23368.1; -; Genomic_DNA.
DR RefSeq; XP_002340755.1; XM_002340714.1.
DR AlphaFoldDB; B8LYL0; -.
DR STRING; 441959.B8LYL0; -.
DR GeneID; 8102287; -.
DR VEuPathDB; FungiDB:TSTA_067960; -.
DR eggNOG; KOG2321; Eukaryota.
DR HOGENOM; CLU_009923_0_1_1; -.
DR InParanoid; B8LYL0; -.
DR OMA; CFDSEVT; -.
DR OrthoDB; 152730at2759; -.
DR PhylomeDB; B8LYL0; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR040382; NOL10/Enp2.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR14927:SF0; NUCLEOLAR PROTEIN 10; 1.
DR PANTHER; PTHR14927; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 550..578
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 507..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..615
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 648..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..698
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..738
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 747 AA; 83638 MW; 025427D8279E3FFF CRC64;
MKISTQSSVP VYTISGSSTA RPLPEWLARR RKRSLKNDPE YANRVELLQD FEFEEASQCI
RISEDGQWVM STGTYKPQIH THYLPHLSLS FARHTVSLNT TFLLLSSDYS KSLHLQADRS
LEFHTPSGCH YTTRLPRYGR DLIYDRQSTE ALVPSVGVNQ DGLGEVFRLN LEAGRYMRSY
EVDVGGDDYT SAGGGALQGG INTGSINTGA IAEGSHNLLA FGTSIGTVEL WDSRARGRAG
ILLPPAQSQP GEGRHEITAL EFHRSGLTLG TGSSNGLIHL YDLRSPIPFL KKDQGYGYPV
HTLKFLQSSS QTREQTMEPK ILSSDKRIIK IWDPRNGTPW TSVEPAVDIN SVAWYPDSGM
ILTANEGRQQ HAFFVPQLGP APKWCSFLDN LVEEMAEDPN DPQAFTGGQT STVYDNYKFL
TVPQLRTLNL DHLIGRTNLL RPYMHGYFVA QRLYEEARLI TNPYIWEEER AKRVKEKIDQ
ERESRIRGKK KVAVKVNRKL AEKLLEKQEK AERRNAKRVL EQGGDETMAE APEQSPETTT
GDESKGLLGD SRFAKLFEDE EFAVDETSRE FQMLNPSTTV EKPERKERGL TAVEQEEADE
IPGSSSDDDD NDSDDAGSEQ GQKPSNRPAK ANQPKMGEEI SYKRSRKPYT KMQVSSSSSS
ANKSRGGGRD RSFETLAHKL GSNNTHRVNK DRATSRQGAV GEKEITFAPT SSKSRSQQQS
RSDYSGTDNG YRNKARRSAS GNTFRRI
//
