ID   B8M5D8_TALSN            Unreviewed;       645 AA.
AC   B8M5D8;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 65.
DE   SubName: Full=GAF domain nucleotide-binding protein {ECO:0000313|EMBL:EED19744.1};
GN   ORFNames=TSTA_030130 {ECO:0000313|EMBL:EED19744.1};
OS   Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS   1006) (Penicillium stipitatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441959 {ECO:0000313|EMBL:EED19744.1, ECO:0000313|Proteomes:UP000001745};
RN   [1] {ECO:0000313|Proteomes:UP000001745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC   {ECO:0000313|Proteomes:UP000001745};
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
CC   -!- SIMILARITY: Belongs to the free Met sulfoxide reductase family.
CC       {ECO:0000256|ARBA:ARBA00038454}.
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DR   EMBL; EQ962654; EED19744.1; -; Genomic_DNA.
DR   RefSeq; XP_002480178.1; XM_002480133.1.
DR   AlphaFoldDB; B8M5D8; -.
DR   STRING; 441959.B8M5D8; -.
DR   GeneID; 8106580; -.
DR   VEuPathDB; FungiDB:TSTA_030130; -.
DR   eggNOG; ENOG502RXXR; Eukaryota.
DR   HOGENOM; CLU_516979_0_0_1; -.
DR   InParanoid; B8M5D8; -.
DR   OMA; KWEGEVM; -.
DR   OrthoDB; 3716715at2759; -.
DR   Proteomes; UP000001745; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd12193; bZIP_GCN4; 1.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   InterPro; IPR000614; FRMsr_CS.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   PANTHER; PTHR21021:SF15; FREE METHIONINE-R-SULFOXIDE REDUCTASE; 1.
DR   PANTHER; PTHR21021; GAF/PUTATIVE CYTOSKELETAL PROTEIN; 1.
DR   Pfam; PF07716; bZIP_2; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   SMART; SM00338; BRLZ; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF57959; Leucine zipper domain; 1.
DR   PROSITE; PS50217; BZIP; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
DR   PROSITE; PS01320; UPF0067; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001745}.
FT   DOMAIN          581..644
FT                   /note="BZIP"
FT                   /evidence="ECO:0000259|PROSITE:PS50217"
FT   REGION          253..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          497..589
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          599..640
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        253..305
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..556
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   645 AA;  70587 MW;  4C16FDC900AE0E08 CRC64;
     MVSRLNPHAD SSYFAAGASK EQVYDQVLEQ ATGLVTGQRN WVRTPRHRTS IKLDEGKETN
     TDSNLANVSS LLWHAYASLP KPSSAVNWAG FYVRDDLFPL LASPKRSNSI SGLTTTTIST
     SYASHHDKKL LLGPFQGKPA CQEIRFGRGV CGTAAQKKET VVVPDVLEFP GHIACDADSR
     SEIVVPILFE GETVAIIDID CTEPAGFDEV DKKYLEQLAQ LLADTPLYSL VTDPSQYQIY
     KVNTAPLHSP VTAQLKKGQS ASSLPSSSLL QTIKGPPKNN HIDSAQRRTI SSSLSTSTIS
     SLWSADPPES PVPPWSAHST TSLSKEIYSS DHQDHSVLLQ QQHSGRHQQE PQQQQQQQQA
     ALFDFSLFEH DSLNSSLQGA CAAPDSTLDQ FTGALDLDLL IDPTSAESQL SFDFLLDFGS
     DQGHPFDITT TSLAIPSKPA TSIQATPSIT IVEDLSSACS PANMPDGGSI LAPSVDLVNM
     NMEHFYPSNT TSVSPNMASI PSRGCPPLVT QFQKQQQPLL APKQHTPPSS SVSPALSHIH
     SIDLDISNSN TMQAPKSKKR SRAESTGLDL SSNNSAQDSE EERIVEKRRR NTMAARRFRQ
     RKQNHVSELE SQLSKVTKER DDLRLQVAKW EGEVMALRKL LEMKK
//