ID   B8M5H3_TALSN            Unreviewed;      1199 AA.
AC   B8M5H3;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 68.
DE   RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN   ORFNames=TSTA_030450 {ECO:0000313|EMBL:EED19779.1};
OS   Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS   1006) (Penicillium stipitatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441959 {ECO:0000313|EMBL:EED19779.1, ECO:0000313|Proteomes:UP000001745};
RN   [1] {ECO:0000313|Proteomes:UP000001745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC   {ECO:0000313|Proteomes:UP000001745};
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR005719}.
CC   -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00005917}.
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DR   EMBL; EQ962654; EED19779.1; -; Genomic_DNA.
DR   RefSeq; XP_002480213.1; XM_002480168.1.
DR   AlphaFoldDB; B8M5H3; -.
DR   STRING; 441959.B8M5H3; -.
DR   GeneID; 8101724; -.
DR   VEuPathDB; FungiDB:TSTA_030450; -.
DR   eggNOG; KOG0964; Eukaryota.
DR   HOGENOM; CLU_001042_5_0_1; -.
DR   InParanoid; B8M5H3; -.
DR   OMA; DQHQSMR; -.
DR   OrthoDB; 231904at2759; -.
DR   PhylomeDB; B8M5H3; -.
DR   Proteomes; UP000001745; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   CDD; cd03272; ABC_SMC3_euk; 1.
DR   Gene3D; 1.20.1060.20; -; 1.
DR   Gene3D; 3.30.70.1620; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR041741; SMC3_ABC_euk.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR   PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF005719; SMC; 1.
DR   SMART; SM00968; SMC_hinge; 1.
DR   SUPFAM; SSF58100; Bacterial hemolysins; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   SUPFAM; SSF75553; Smc hinge domain; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001745}.
FT   DOMAIN          522..634
FT                   /note="SMC hinge"
FT                   /evidence="ECO:0000259|SMART:SM00968"
FT   REGION          640..659
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          186..220
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          267..371
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          406..503
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          673..770
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          794..925
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          973..1000
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1199 AA;  137573 MW;  A4867FBA9D55B1E9 CRC64;
     MYIKQIIIQG FKSYKDQTVI EPFSPKHNVI VGRNGSGKSN FFAAIRFVLS DAYTQMGREE
     RQALLHEGSG SAVMSAYVEV IFDNSDERFP TGKPELVLRR TIGLKKDEYT LDHKNATKAD
     VMNLLESAGF SRSNPYYIVP QGRVTTLTNM KDSERLVLLK EVAGTQVYEA RRAESLKIMN
     ETNNKRAKID ELLDYINERL GELEEEKDEL RNYQEQDRER RCLEYTIYSR EQQEIANALD
     SLEGQRQTGV EDTDVNREHF IQGEKDITQI DSEIAECKQQ IEFLKVDKTQ LEDERREAFR
     ALAQVELQEK ALKDNQSAAQ EMKARHENEL NAVQTAISQR ESELQTILPQ FNAAKEQEDA
     VKLQLEQAET SRQRLYAKQG RNSRFKSKSE RDKWLQKEIQ ETKNSIKAVN AVKAQTTEDI
     QDLQKTIASL EPEIEKLRKQ IDGRGDAIQS IEQEIQNAKD ERDRLMDQRK ELWREEARLD
     SILSNSSQEV DRAERNLSHM MDNNTSRGIA AVRRIKRQHN LDGVYGTLAE LLEVNERYRT
     AVEVTAGTSL FHYVVDTDET ATKVLEILQK ERAGRVTFMP LNRLKPRPTN VPKASDTIPM
     IEKLQYDPQY EKAFQQVFGK TIICPNLQVA SQYARSHGVN AITPEGDRSD KRGALTGGFH
     DSRQSRLEAV KALTKWRDEY ESKKNRASEI RKDLEKLDQQ VTRAVGELQK LEQRKHQFHG
     NSGPLRQELR NKRELLQNKN DNLDAKQRAL RNIENNLTAL EGQVGTLEAE ISSGFQKALT
     AEEEKELESL GITAQTLRRQ YTDLSSKRSE LEARKSVLEV ELRENLYPRL DQLSNPDTDM
     GDDNTQGTLK EARRQMKKLQ EALGKITHRL AEVDQSISEG NAQVAQLENR KSEVRNNLEA
     LAKSIEKHQR RMEKSMQKKA ALTKQAAECS ANIRDLGVLP DEAFTKYSKT DSNTVVKKLH
     KVNESLKKYS HVNKKAFEQY NNFTKQRETL TKRREELDAS QKSIDELIMV LDQRKDEAIE
     RTFKQVSREF HNVFEKLVPA GRGRLIIQRK TDRALRTDND LESEDEDRHE SVENYVGVGI
     SVSFNSKHDE QQRIQQLSGG QKSLCALALV FAIQACDPAP FYLFDEIDAN LDAQYRTAVA
     QMLQSISDST NGQFICTTFR PEMLHVAEKC YGVSFRNKAS TIDVVSKEEA LKFVEEQKS
//