ID B8MHJ1_TALSN Unreviewed; 533 AA.
AC B8MHJ1;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=TSTA_010880 {ECO:0000313|EMBL:EED15972.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED15972.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
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DR EMBL; EQ962656; EED15972.1; -; Genomic_DNA.
DR RefSeq; XP_002483206.1; XM_002483161.1.
DR AlphaFoldDB; B8MHJ1; -.
DR GeneID; 8109861; -.
DR VEuPathDB; FungiDB:TSTA_010880; -.
DR eggNOG; KOG1075; Eukaryota.
DR HOGENOM; CLU_000680_30_2_1; -.
DR InParanoid; B8MHJ1; -.
DR OrthoDB; 2169149at2759; -.
DR PhylomeDB; B8MHJ1; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd09276; Rnase_HI_RT_non_LTR; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001745}.
FT DOMAIN 199..336
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
SQ SEQUENCE 533 AA; 59714 MW; 157D240A89133C50 CRC64;
MDGRDFLLVP WDLQRSRGEL ATVKSTVRWL GILLDNQLTW KSHYNARIKT ARNTIIRLNS
LCRANGLPPA LVRRIQKATV QAQLLWGAEI WWQGQKTWAQ RIQILINKQA RAQILPVTLR
HGDLHAQPGE QPLDDREWAS RDNKVLNRLG QRLAKHLAQR LNRDPSGGIE RTERCELKSF
PGSIRVLDKE EALTEANQQR AGTTFWSDGS RLDTGRAGAG VTLQAVPGGP WEHVEVPMGH
GHEVFDAELV GVATALEWAL ERQPLDPIWV FLDAQNAIDR LRSTRPGPGQ ALVLRAHKAA
EKLALRGQPV TIQWVPGHSG IEGNEQADQA AKRAASKQTA PGFEHLSLAH VRRACTEARR
AAVSEWAQIN AVQGRHRDGR VYKMPRGWNL DPVAGKAPKR LASRYYQLKT GHAPIGTYLY
RIGRRESPEC QACKEPHETV RHVLFECRGR RTGRRTLYQA LKKAGVPLPT AAEEDPEARL
FAEPRATQGL LQFVAEANLF NDKERTAREA ESSDAWGWDT LEEGGLGVTL EDE
//
