ID   B8MJA8_TALSN            Unreviewed;      1123 AA.
AC   B8MJA8;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Polymerase, putative {ECO:0000313|EMBL:EED14697.1};
GN   ORFNames=TSTA_041740 {ECO:0000313|EMBL:EED14697.1};
OS   Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS   1006) (Penicillium stipitatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441959 {ECO:0000313|EMBL:EED14697.1, ECO:0000313|Proteomes:UP000001745};
RN   [1] {ECO:0000313|Proteomes:UP000001745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC   {ECO:0000313|Proteomes:UP000001745};
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; EQ962657; EED14697.1; -; Genomic_DNA.
DR   RefSeq; XP_002484650.1; XM_002484605.1.
DR   AlphaFoldDB; B8MJA8; -.
DR   GeneID; 8102951; -.
DR   VEuPathDB; FungiDB:TSTA_041740; -.
DR   eggNOG; KOG1075; Eukaryota.
DR   HOGENOM; CLU_000680_11_2_1; -.
DR   InParanoid; B8MJA8; -.
DR   OMA; WERNEED; -.
DR   OrthoDB; 2284953at2759; -.
DR   PhylomeDB; B8MJA8; -.
DR   Proteomes; UP000001745; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR   PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14529; Exo_endo_phos_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001745}.
FT   DOMAIN          915..1123
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          86..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          810..830
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..113
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        114..140
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1123 AA;  124902 MW;  2B243BB2B1EB1A99 CRC64;
     MARNRSEPDK RSLQNVLQEI TTAATTRAAE GQKIFSPIAA FLDKHRNQTA GLSPYLQGAL
     AALSDDLATV AQHHFNAYIS GITPTPSTHS PAPALSPIPS PLPPTPPPSY PPSGLAQSSY
     TTITKSNPAR SGTAIKQTKP PTKKPTPDVK QSLPDYRLFV RLPIDHAAKM MDSYAIYTSL
     RAQLGINSNA LKEVQTTKTR FALYPATMEA LSTLEAQKEV ISTYFGNCQV ERSARWISYR
     VTNLPRKIGQ ITNGQYSMIP VDPATLSTEI AEQTGYRPIS VSETTASAAN VNSPSSSWFI
     NFSEDSKASL STWLRLFGTI TNARFLTRKV TIIQCNRCWK WHNARSCARS PRCRLCGLSE
     HIEEEHNNSC STPNPYCYPP RCFYCHGPHP ADFTDCPLRP KAGTTRTKAQ RAEIRKTCAI
     NLAKARTEQG CSSESSATTQ EQHMVIDTPP TQIQVASPFR PTTPPPPAPS QEPPVTASVE
     PYIFSNLSQK ITKRHPSYEC FSPTDSWTVT RRPCVLTYVW KNAGLQASQL RPIITDPATL
     SDLLFLQISS STGQSVLTIN AYNAPAGSTR AGKAMETLIS LPETLFLQPT LLAGDFNLLH
     IRWQPSLTYR PAVSADPFIE WLDHLGFILT LEIDCPTHTR GNVLDLTYAT SLLALSGLHT
     STAPHLDSTS DHTPLLTTIP WDQRHTLPTQ KIRFDILDQP LFLSLLSTNL SQIQPLDSLK
     ANLESLAQGL TSAIHSAYEG SAKRSLPHKK GQPWWNPECK EALQAYRSEL LPKEEFRSTI
     RKTQREFWRN KLITASQTKE VFDISKWHKS RGSYRSPPLK DPLRPDNPPA VSVQEKRDLL
     VRNLLQNTTE AGDIPLDCPA VPTTTLPFPE ITMAQVEKSI LKARNTAPGE DELQTNILKT
     AWPLIKDKIL FLFQGCLRLG YHPKYFRHAI LTILQKPSKE DWTNPRSYRP IALLSVLGKG
     LECLVARNMA WIAIYYKVLA SQQFGALPLR SAIDLTTCLT HDIEQALNQG KTASLLTFDV
     EGAFDNVLPG RLTYRLRTQG WPNNLILWIS SFITERTIQI RFDNELGPHT DISCGLPQGS
     PISPILFMLY IAPLFHMGNP RTRFGYADNR ATLAISPSLL TNC
//