ID B8MKT1_TALSN Unreviewed; 359 AA.
AC B8MKT1;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Kynureninase, putative {ECO:0000313|EMBL:EED14930.1};
DE EC=3.7.1.3 {ECO:0000313|EMBL:EED14930.1};
GN ORFNames=TSTA_043970 {ECO:0000313|EMBL:EED14930.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED14930.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
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DR EMBL; EQ962657; EED14930.1; -; Genomic_DNA.
DR RefSeq; XP_002484883.1; XM_002484838.1.
DR AlphaFoldDB; B8MKT1; -.
DR GeneID; 8097905; -.
DR VEuPathDB; FungiDB:TSTA_043970; -.
DR OrthoDB; 5471916at2759; -.
DR PhylomeDB; B8MKT1; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030429; F:kynureninase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR GO; GO:0006569; P:tryptophan catabolic process; IEA:InterPro.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR010111; Kynureninase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR NCBIfam; TIGR01814; kynureninase; 1.
DR PANTHER; PTHR14084; KYNURENINASE; 1.
DR PANTHER; PTHR14084:SF2; KYNURENINASE 2; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF038800; KYNU; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EED14930.1};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745}.
FT DOMAIN 217..305
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 359 AA; 39756 MW; 9E57E3EF768AD7F3 CRC64;
MAPSLIAPVS PSSEETIHRM EATKFIPTSY PSNAQTREYA ESLDQADTLR SFRDKFIIPS
KANLKATKLA KPGLSADESI YFCGNSLGLQ PRATSAYIQA QLDTWSSIGV NGHFRDLEDS
PLKSWQLLAE QAAGDMALIV GASPEEIAAM GTLTANLHLL LASFYKPTES KHKILLDWKA
FPSDHYAIES QIAWHGRKPS ESMVLIGPDE GEYIISTEKI LSIIDEHASK TALLLLPGIQ
YYSGQLFDIP TITKHAQARG IIVGWDLAHV YANVDVKLHE WNVDFAAWCT YKYGNAGPGA
IGGAFVHERH GTVDYSQGED KPVFRHRLTG WYGGDRSVRF KMDNSQFPSS NWYDCSVLT
//
