ID B8MQU0_TALSN Unreviewed; 335 AA.
AC B8MQU0;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=O-methyltransferase, putative {ECO:0000313|EMBL:EED12775.1};
GN ORFNames=TSTA_052940 {ECO:0000313|EMBL:EED12775.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED12775.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
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DR EMBL; EQ962659; EED12775.1; -; Genomic_DNA.
DR RefSeq; XP_002486886.1; XM_002486841.1.
DR AlphaFoldDB; B8MQU0; -.
DR GeneID; 8098243; -.
DR VEuPathDB; FungiDB:TSTA_052940; -.
DR HOGENOM; CLU_005533_5_0_1; -.
DR OMA; NTMGARK; -.
DR OrthoDB; 1067404at2759; -.
DR PhylomeDB; B8MQU0; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF1; HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EED12775.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:EED12775.1}.
FT DOMAIN 170..313
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 242
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 335 AA; 37482 MW; 5DDA70BE87747812 CRC64;
MIAVAARVAV DLDLFRHVVN EGPVTSTRLA ELCGAEELLI IRLMRPLSAT HFVEETGPRT
WKATQITAAM ATEEIAAGHR MISQLIVPAM QKAPDYLVKH GYSCPIDPRD GLVQHAFLTK
ATTFERITSS PSLLKDFNTF MGNTMGARSY WVDWYPVQTQ ILDNADPEKP LIVDVGAGKG
HDLLAFHARF PDHAGKLVLQ DLPPVIEVLD ALNPVIEKVA YDFFTEQPVK GARVYFYHHI
LHDWSDSYCL DILRRVVSAM TPGYSKLLLH EMIVLEEGAP QFQAQLDMTM MAFNSGMERT
AKQWSELLES VGLRVVRVWE PIEEGADGIV EAIKD
//
