ID   B8MVG2_TALSN            Unreviewed;      1503 AA.
AC   B8MVG2;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Polymerase, putative {ECO:0000313|EMBL:EED11470.1};
GN   ORFNames=TSTA_007600 {ECO:0000313|EMBL:EED11470.1};
OS   Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS   1006) (Penicillium stipitatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441959 {ECO:0000313|EMBL:EED11470.1, ECO:0000313|Proteomes:UP000001745};
RN   [1] {ECO:0000313|Proteomes:UP000001745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC   {ECO:0000313|Proteomes:UP000001745};
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; EQ962663; EED11470.1; -; Genomic_DNA.
DR   RefSeq; XP_002488786.1; XM_002488741.1.
DR   STRING; 441959.B8MVG2; -.
DR   GeneID; 8103289; -.
DR   VEuPathDB; FungiDB:TSTA_007600; -.
DR   eggNOG; KOG1075; Eukaryota.
DR   HOGENOM; CLU_000680_23_0_1; -.
DR   InParanoid; B8MVG2; -.
DR   OMA; CSARWIS; -.
DR   OrthoDB; 2202746at2759; -.
DR   PhylomeDB; B8MVG2; -.
DR   Proteomes; UP000001745; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR   PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14529; Exo_endo_phos_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001745}.
FT   DOMAIN          818..1078
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          89..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          713..733
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..27
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..113
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1503 AA;  167052 MW;  E675662998FF4DA5 CRC64;
     MARNRSEPDK RSLQNVLQET TTAATTRAAK GQKIFSPIAA FLDKHRNQTA GLSPYLQGAL
     ATLSDNLATV AQHHFNAYIS SITSTLSTHS PAPALSPIPS PLPPTPPPSC PPSGLTQSSY
     ATITKSNPAR SDHATKMIDS YAIYTSLRAQ LGINSNALKE VQTTKTRFAL CPATMEALST
     LEAQKEVIST YFGNCQVECS ARWISYRVTN LPRKIGQITN GQYSMIPVDP ATLSTEIAEQ
     TGYRPISVSK TTASAANVNS PSSSWFINFS EDSKASLSTR LHLFGTITNA CFLTRKVTII
     QYNHCWKWHN AQSCAQSPRC RLCGSLEHIE EEHNNSCSTL NPHCCPLRCF HCHGPHLADF
     TDCPLRPKAG TTRTKAQRAE IRKTCAINLA KARTEQGCSS ELSATTQEQH MVIDTPPTQI
     QVASPFRPTT PPPPAPSQEP PVTASVEPYI FSNLSQKITK RHPSYECFSP TDSWTVTGRP
     RVLTYVWKNA GLQASQLWPI ITDPATLSDL LFLQIFSSTG QSVLTINAYN APAGSTRASK
     AMETLISLPE TLFLQPTLLT GDFNLLHIRW QPSLTYRPAV SADPFIKWLD HLGFILISEI
     DCLTHTRGNV LDLTYATSSL ALSRLHTSTV PHLDSTSDYT LLLTTIPWDQ RHTLPTQKIR
     FDTLDQPLFL SLLSTNLSQI QPLDSSKANL ESLAQGLTSA IHKVFDISKW HKSRGSYRSP
     PLKDPLRPDN PPAVSVQEKR DLLVRNLLQN TTEAGDIPLD CPAVPTTTLP FPEITMAQVE
     KSILKARNTA PGEDELQTNI LKTAWPLIKD KILFLFQGCL RLGYHPKCFR HAILTILQKP
     SKEDWTNPRS YRPIALLSVL GKGLERLVAQ NMAWIAIHYK VLASQQFRAL PLRLVINLTT
     CLTHDIEQAL NQGKTASLLT FDVEGAFDNV LPGRLTYWLR TQGWPNNLIL WISSFITERT
     IQIRFDNELG PHTDISCGLP QGSPISPILF ILYIAPLFHM GNPRTRFGYA DDGATLAISP
     SLLTNCQTLS ESLQDAIEWG TAEGITFAPN KYELMHFSRH RADQDPATTP SVLMGSVTVT
     EATDQMTSKV LTIASALRSL GNTVHGMRPH LLQQAISACV LRKVYFGAET WWPGRTRFRS
     RPQADTPPIS NLVNKHLTDL STVILTGARA ILPVFRTTQL PVLHRESGFY PPKIELDQIA
     LTASTRLSRL DPYHPLRRRA RAIARTGHPT SRFARRVLAL PNMEKINPLL HPPWSTKEPR
     EAALRWVGAP SGRTREEAAD NFQILLQSIP NNDIIIYSDG SKLENGQTGG GYVGSSQAIF
     ESFNTLAATW PSRRRLLQIE RHANIPRNEA ADYAAKEGAG KTVPISHPWS YAAFKRHTKS
     QAASRAQTYW QAAAPRPPEL QLPRHILGRI LAARTKHGDF ADYHEWFNHT DAHLTCRCGA
     RKSPIHFIFC QIAKRKAPRF PRHPSEVIPF LLGTPKGATK LAKWLTETRF FEDICPRRPP
     LST
//