ID B8MZY7_ASPFN Unreviewed; 1230 AA.
AC B8MZY7;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE SubName: Full=Nuclear import and export protein Msn5, putative {ECO:0000313|EMBL:EED57929.1};
GN ORFNames=AFLA_086270 {ECO:0000313|EMBL:EED57929.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED57929.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED57929.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
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DR EMBL; EQ963472; EED57929.1; -; Genomic_DNA.
DR RefSeq; XP_002373541.1; XM_002373500.1.
DR AlphaFoldDB; B8MZY7; -.
DR STRING; 332952.B8MZY7; -.
DR EnsemblFungi; EED57929; EED57929; AFLA_086270.
DR VEuPathDB; FungiDB:AFLA_004210; -.
DR eggNOG; KOG2020; Eukaryota.
DR HOGENOM; CLU_003712_0_0_1; -.
DR OMA; IAKRSWG; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045478; Exportin-5_C.
DR InterPro; IPR045065; XPO1/5.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF3; EXPORTIN-5; 1.
DR Pfam; PF19273; Exportin-5; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 107..183
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 330..1177
FT /note="Exportin-5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19273"
FT REGION 1004..1023
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1230 AA; 139273 MW; 7A3905B4E94CE441 CRC64;
MTTEEDLSES RIADIVRALE LIHNPSSTNE LRREALTFVE SQKESKSAAR NGFVLASREQ
NDPLVRYFGL TLLDHVLRHT SFTGSAQVVE LRELVLKLAE SIRPEDPAYL RNKIPQLWAE
IAKRSWGLDW IEMDQALAQF WGASLVHKEL VLSILETLSE DIFYREDTVS SLRGTDLNRA
LVEIFTPLSV FEEVYPKRDN HVALRYGSDG WLPRICEFLQ YCVENLQNSK QAKDAALKAL
AALKSVLLWA IPKAIISSNC VPAIARAFTC SDEQVLLAAV EALHSLYSRS NMDMESFQPL
VHLMYETESL DIMQKLYQWS IVGPDDIDDT RYMISKKLSE MLSYIAGFLE EKGFSLESAH
GMNLPFFFHL TISVIQHQSL MVSIPVLHVW SKLLASERIG NTDLVTGLIP SLLEICTQRL
VRWEALPTDS DDPTVAFLND DIDTVPERHA FVGNYRRYCS SIIETIVQKR PQEAIPHILS
GVDTNLNNLY NGVEPFNAKS FSKSSIPLMR ADTQFAVVEA TLKGYNKWVS AHGKMPQQDE
QKRSDLEGIL EKWAFSLMQR SFEDPILKQR VIKLIVDISS KALDKTPSFA LKVLEYILMT
RLPDQPEFPA YSEAVKELHG LSSHELRRLA MRYSEYFATF YDVLEPKVKE ISLANRVDDK
LQMELTSILL IIMQRANNVE PFLRQSRLAS FIEPIRQAWQ DEEFRQMSSS FEGFCSMLGL
QSVGPFMQAQ QAQKLEDWAS VPLDSEGKRI QEEMTRKFQQ LPLRGTKTML AVSTDKLKKN
EPAYELACNV WHETIPIILP TLLELVSNAH AFHNPANWGG LPSEMQTVVE RILTDRFWQA
GISTGSRDEF YAKITASRAS LEGFASSVRG KIRAVRESCY SMLYSMSRLR EHFYGFAELP
GPLSQALFKD SSCLSSHQFS VLLNISRCLI DDCPVRFRGH FLPPMLATLF TNIDKKVTSE
WAIIEQQREG LADADLTDEM KSESILRQLT YSAVIMVASL LDPQRGDPDE EPADPSAPHP
QPALSDSIRH FVLSSPEIFE PLMLFCTHAL RMRDTRCCSI ITRVIRSILQ DFAPPNNSPT
TVQIREFICS EVLKACITSV HEPYFVDMQK DLAQLISSIW VLYGSSTPTP RSVILSLPGM
DEQRVAMTEA SLVRSTAARQ QRALILDLLE GLRGVSIAEQ GKILGSREER RKARSALQER
YMTAEMEGQQ NNKVDINDGP DLTGVADMFG
//
