ID   B8N3U2_ASPFN            Unreviewed;       835 AA.
AC   B8N3U2;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Glutaminase, putative {ECO:0000313|EMBL:EED55904.1};
GN   ORFNames=AFLA_031760 {ECO:0000313|EMBL:EED55904.1}, G4B84_003350
GN   {ECO:0000313|EMBL:QMW28061.1};
OS   Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS   / JCM 12722 / SRRC 167).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=332952 {ECO:0000313|EMBL:EED55904.1, ECO:0000313|Proteomes:UP000001875};
RN   [1] {ECO:0000313|EMBL:EED55904.1, ECO:0000313|Proteomes:UP000001875}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC   SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC   {ECO:0000313|EMBL:EED55904.1};
RX   PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA   Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA   Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT   "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT   aflatoxin contamination of food and feed.";
RL   Genome Announc. 3:E0016815-E0016815(2015).
RN   [2] {ECO:0000313|EMBL:QMW28061.1, ECO:0000313|Proteomes:UP000515286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW28061.1,
RC   ECO:0000313|Proteomes:UP000515286};
RA   Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA   Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA   Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA   Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT   "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT   Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT   Aflatoxin Production.";
RL   Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; EQ963473; EED55904.1; -; Genomic_DNA.
DR   EMBL; CP059867; QMW28061.1; -; Genomic_DNA.
DR   RefSeq; XP_002374686.1; XM_002374645.1.
DR   AlphaFoldDB; B8N3U2; -.
DR   STRING; 332952.B8N3U2; -.
DR   EnsemblFungi; EED55904; EED55904; AFLA_031760.
DR   VEuPathDB; FungiDB:AFLA_001045; -.
DR   eggNOG; ENOG502QPQS; Eukaryota.
DR   HOGENOM; CLU_008020_1_0_1; -.
DR   OMA; WTGYLVR; -.
DR   OrthoDB; 3715424at2759; -.
DR   Proteomes; UP000001875; Unassembled WGS sequence.
DR   Proteomes; UP000515286; Chromosome 2.
DR   InterPro; IPR014870; GtaA_C.
DR   InterPro; IPR032514; GtaA_central.
DR   InterPro; IPR033433; GtaA_N.
DR   PANTHER; PTHR31987; GLUTAMINASE A-RELATED; 1.
DR   PANTHER; PTHR31987:SF12; PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10910)-RELATED; 1.
DR   Pfam; PF08760; DUF1793; 1.
DR   Pfam; PF16335; DUF4965; 2.
DR   Pfam; PF17168; DUF5127; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..835
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5036437627"
FT   DOMAIN          122..347
FT                   /note="Glutaminase A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17168"
FT   DOMAIN          354..474
FT                   /note="Glutaminase A central"
FT                   /evidence="ECO:0000259|Pfam:PF16335"
FT   DOMAIN          534..577
FT                   /note="Glutaminase A central"
FT                   /evidence="ECO:0000259|Pfam:PF16335"
FT   DOMAIN          583..776
FT                   /note="Glutaminase A C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08760"
SQ   SEQUENCE   835 AA;  92447 MW;  D775FF4969783F6C CRC64;
     MRLSFTVLTA ALQAAVSTAS TLTPPVLPLI VRNPYLSTWF GNAREAPWSK WPMFYTGEEV
     GLSLMAHVPS TGTVYPLLGK PHESLPSDSD SPEVAFPVYL GANYDASTTN LTYRINSDTS
     ASTPLDITLS FLSPITPTST LRQSIPASYV TIHVHGDVAV NVYMDVNGRW VSGDAGSKIT
     WQYDGFDAKG GKPTLQRWRF KRETELLLSE IRDRAEWGTL HFTGPANVQF QSGEALAVRR
     GFAAEGALRN ENDGAFRAVG DREPVFAFSK SFIPSKKSGP ASDSVTFTLA LIQDPVVQYA
     SSRGLTLMRP LWRSWFSNEE ALLSFHYHDL ANAGTLASDY SEQLAQDAYQ SGAYDYVDIV
     ALSARQVMGA TTFAGTPENP ILFLKEISSN GNFQTIDVIF PSFPFFLYTN PRWLAYLLEP
     LIEHMLSGQY PNKYAMHDLG THFPNATGHP DGNDEYMPVE ECGNILIMGL AVVNSLRYSA
     DSTAASVWST RGTAAQTSDK NSGYFPLDNL QALGGIDKQD GRWGGGAQGE HLAEKWVQRS
     YKLWTQWTSY LVEFSLEPAN QLSTDDFAGW LALQTNLALK GIIGINAMSK LAEVAGHKAN
     ASYYKNIADT YIAKWEEFGM SRDGTHAKLA YDWYGSWTTI YNLYADAQLC FHLEGTDISP
     AHGSQKSLHS HSGKSGFVPH HIYQKQSIWY HYVRQKYGLP LDSRHLYTKT DWEFFSMAVA
     SEDVRSEILE SVARWVNETV TDLPFTDLHN TEGKGEFPGP NFFARPVIGG HFAFLALQRA
     CEGRAMEGLA FLNGKPGFGD DSVASAETLS QWEAMAAKAA EKFKFDGYES ERVEL
//