ID B8NE03_ASPFN Unreviewed; 816 AA.
AC B8NE03;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=DUF803 domain membrane protein {ECO:0000313|EMBL:EED51471.1};
GN ORFNames=AFLA_057340 {ECO:0000313|EMBL:EED51471.1}, G4B84_007990
GN {ECO:0000313|EMBL:QMW32559.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED51471.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED51471.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC {ECO:0000313|EMBL:EED51471.1};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
RN [2] {ECO:0000313|EMBL:QMW32559.1, ECO:0000313|Proteomes:UP000515286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW32559.1,
RC ECO:0000313|Proteomes:UP000515286};
RA Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT Aflatoxin Production.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; EQ963477; EED51471.1; -; Genomic_DNA.
DR EMBL; CP059870; QMW32559.1; -; Genomic_DNA.
DR RefSeq; XP_002378478.1; XM_002378437.1.
DR AlphaFoldDB; B8NE03; -.
DR EnsemblFungi; EED51471; EED51471; AFLA_057340.
DR VEuPathDB; FungiDB:AFLA_004781; -.
DR eggNOG; KOG2922; Eukaryota.
DR HOGENOM; CLU_012349_2_1_1; -.
DR OMA; VMQIRYI; -.
DR OrthoDB; 2906343at2759; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR Proteomes; UP000515286; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF93; DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070); 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 474..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 785..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..598
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 797..816
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 816 AA; 88640 MW; 88A843671FF9D626 CRC64;
MAHLHEVPLA AGLLTTFVPS AVPTLTLSSL YVSPSSQPFP TLASDPGYDD GGGGGGGMHE
WSSLIGIVTA LIGNILISLA LNIQRYAHIR IEREWEHQKL QKEAEWKRAN PGLGSTDTYG
SVADHEYNDY ETRGRNQSRR FARYRDESPE VRFVHHDQPH IDLGPEDDDE MDTNAHQDQM
DESFMSDRTV RPGDLRRKSY LRSPYWWVGI VLMCVGEIGN FMAYGFAPAS IVSPLGVVAL
ISNCVIAPIL LKEKFRGRDF WGVVVAVTGA VVVVLSASSS EEKIGPHDIW VMITRWEFET
YVGISTVLII GLLWASGKYG SRTVLIDVGL VALFGGYTAL STKGVSSLLS FTLWHVITFP
ITYLLVFVLV FSAVLQIRYI NRALQRFDST QVIPTQFVLF TLSVIIGSAV LYRDFENYTL
DRAGKFVGGC LLTFLGVYFI TSGRVRNDDE SSYSNDEEEA IGLLAGERYR DSVDMSPPAR
HVRVQKPSRI PLETQAENMQ SPSGSLLSHG IEGIDEGQRT PRGVSSAAPS SPVGSLTADS
LTGQSLQPSP PMHPNSLLTN PWADAHESAI ETPKSEPQIP QIDRPVTPEQ SRPTTSGSPV
LLRFPPAPGI EDNNLKVPAA SGTETASPGI RSSTVPQTPP ARRLRNSISS RFSPGPLLPT
ISAGFSAVVA ESLRRGETSP VKDRKSMRRH RGKQLSTTIV DGFLRSRDGE NANIDEGLGP
RGVLPTARFN STGDIATAPV TAGQSTTTLD TEDAPQNLQP DGSTSVSRIR SLSDSWSGGL
AWLGGTLRKV NGHGNGHEQI AESQTNEEET GANTQA
//
